Piccolo Data

## Overview

Piccolo Data is a dataset for object detection tasks - it contains Polyps annotations for 219 images.

## Getting Started

You can download this dataset for use within your own projects, or fork it into a workspace on Roboflow to create your own model.

  ## License

  This dataset is available under the [CC BY 4.0 license](https://creativecommons.org/licenses/CC BY 4.0).

Protein-Protein, Genetic, and Chemical Interactions for Fujimoto K (2002):Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis. curated by BioGRID (https://thebiogrid.org); ABSTRACT: We have previously shown that cAMP-binding protein cAMP-guanidine nucleotide exchange factor II (GEFII) (or Epac2) interacting with Rim2 is involved in cAMP-dependent, protein kinase A-independent exocytosis in pancreatic beta-cells. The action of the cAMP-GEFII.Rim2 complex requires both intracellular cAMP and Ca(2+). Although Rim2 has C(2) domains, its role as a Ca(2+) sensor has remained unclear. In the present investigation, we have discovered that Piccolo, a CAZ (cytoskeletal matrix associated with the active zone) protein in neurons that is structurally related to Rim2, also binds to cAMP-GEFII and that it forms both homodimer and heterodimer with Rim2 in a Ca(2+)-dependent manner, whereas Rim2 alone does not form the homodimer. The association of Piccolo.Rim2 heterodimerization is stronger than Piccolo. Piccolo homodimerization. Treatment of pancreatic islets with antisense oligodeoxynucleotides against Piccolo inhibits insulin secretion induced by cAMP analog 8-bromo-cyclic AMP plus high glucose stimulation. These results suggest that Piccolo serves as a Ca(2+) sensor in exocytosis in pancreatic beta-cells and that the formation of a cAMP-GEFII.Rim2. Piccolo complex is important in cAMP-induced insulin secretion. In addition, this study suggests that CAZ proteins similar to those in neurons are also function in pancreatic beta-cells.

This dataset provides information about the number of properties, residents, and average property values for Piccolo Road cross streets in Ruffin, SC.

Protein-Protein, Genetic, and Chemical Interactions for Kim S (2003):The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. curated by BioGRID (https://thebiogrid.org); ABSTRACT: The cytoskeletal matrix assembled at active zones (CAZ) is implicated in defining neurotransmitter release sites. However, little is known about the molecular mechanisms by which the CAZ is organized. Here we report a novel interaction between Piccolo, a core component of the CAZ, and GIT proteins, multidomain signaling integrators with GTPase-activating protein activity for ADP-ribosylation factor small GTPases. A small region (approximately 150 amino acid residues) in Piccolo, which is not conserved in the closely related CAZ protein Bassoon, mediates a direct interaction with the Spa2 homology domain (SHD) domain of GIT1. Piccolo and GIT1 colocalize at synaptic sites in cultured neurons. In brain, Piccolo forms a complex with GIT1 and various GIT-associated proteins, including betaPIX, focal adhesion kinase, liprin-alpha, and paxillin. Point mutations in the SHD of GIT1 differentially interfere with the association of GIT1 with Piccolo, betaPIX, and focal adhesion kinase, suggesting that these proteins bind to the SHD by different mechanisms. Intriguingly, GIT proteins form homo- and heteromultimers through their C-terminal G-protein-coupled receptor kinase-binding domain in a tail-to-tail fashion. This multimerization enables GIT1 to simultaneously interact with multiple SHD-binding proteins including Piccolo and betaPIX. These results suggest that, through their multimerization and interaction with Piccolo, the GIT family proteins are involved in the organization of the CAZ.

Nach INSPIRE transformierter Bebauungsplan „Piccolo-Areal“ der Stadt Burladingen basierend auf einem XPlanung-Datensatz in der Version 5.0.

The development plan (BPL) contains the legally binding settlements for the urban planning order. In principle, the development plan must be developed from the land use plan. The available data is the development plan “Piccolo area” of the city of Burladingen from XPlanung 5.0. Description: Usage: MI.

PENDING SCAN...

For a history and background of this violin, see links below.

The dataset includes:

1. DICOM CT data folders for the violin body (? GB) and neck and scroll (? GB).

Access to the dataset is by permission only, granted by writing to digitalamati.library@gmail.com. The request must be made with an attestation that the request is for personal use only, and not to be sent to anyone else. This constraint is to keep an approximate record of who has use of the data. Abrogations will only compromise the status of the digital library.

Subscribers can find out export and import data of 23 countries by HS code or product’s name. This demo is helpful for market analysis.

This dataset provides information about the number of properties, residents, and average property values for Piccolo Lane cross streets in Springfield, SC.

This dataset provides information about the number of properties, residents, and average property values for Piccolo Way cross streets in Davenport, FL.

Piccolo Mosaic Limited Company Export Import Records. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.

This dataset was archived on 2014-09-12 from the EPD database (http://www.europeanpollendatabase.net).

The Piccolo Latte Coffee market has emerged as a distinctive segment within the specialty coffee industry, captivating coffee enthusiasts and professionals alike with its unique blend of espresso and steamed milk in a diminutive cup. Originating from Australia, the Piccolo Latte is increasingly gaining popularity gl

The datasets and the resulting tables are based on the information contained into the dataset named "Gli autori della letteratura italiana sul grande e piccolo schermo. Initial dataset.".These datasets have been used as means to simplify the task of gathering the data related to different topics. The information related to each topic are collected in the resulting tables.

This dataset was archived on 2014-11-03 from the EPD database (http://www.europeanpollendatabase.net).

Protein-Protein, Genetic, and Chemical Interactions for Buisson R (2010):Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. curated by BioGRID (https://thebiogrid.org); ABSTRACT: Inherited mutations in human PALB2 are associated with a predisposition to breast and pancreatic cancers. PALB2's tumor-suppressing effect is thought to be based on its ability to facilitate BRCA2's function in homologous recombination. However, the biochemical properties of PALB2 are unknown. Here we show that human PALB2 binds DNA, preferentially D-loop structures, and directly interacts with the RAD51 recombinase to stimulate strand invasion, a vital step of homologous recombination. This stimulation occurs through reinforcing biochemical mechanisms, as PALB2 alleviates inhibition by RPA and stabilizes the RAD51 filament. Moreover, PALB2 can function synergistically with a BRCA2 chimera (termed piccolo, or piBRCA2) to further promote strand invasion. Finally, we show that PALB2-deficient cells are sensitive to PARP inhibitors. Our studies provide the first biochemical insights into PALB2's function with piBRCA2 as a mediator of homologous recombination in DNA double-strand break repair.

Microzooplankton monitoring in the Mar Piccolo of Taranto, 2013-2014 in the framework of the Italian flagship project RITMARE.

This dataset provides information about the number of properties, residents, and average property values for Piccolo Drive cross streets in Maricopa, AZ.

The palynological organic matter dataset was obtained from the S05B core retrieved in the Mar Piccolo, a semi-enclosed marine basin located in the Central Mediterranean. The palynological organic matter analyses were conducted on 41 samples (0,08-29,49 m), focusing on both structured and amorphous palynological organic matter. These analyses performed describe the paleoenvironmental and landscape changes during the last ~12,000 years, with particular reference to rapid Holocene climate events, such as the 8.2 and 4.2 ka BP events, and the impact of human activities. […]

Macrobenthos monitoring in the Mar Piccolo of Taranto in June 2013 and April 2014 in the framework of the Italian flagship project RITMARE