Overview with Chart & Report: Markit/CIPS Manufacturing PMI is calculated by Markit together with the Chartered Institute of Procurement & Supply (CIPS). It characterizes the state of the industrial sector. The index is

This dataset provides values for MANUFACTURING PMI reported in several countries. The data includes current values, previous releases, historical highs and record lows, release frequency, reported unit and currency.

Overview with Chart & Report: UK Markit/CIPS Construction PMI is published by MarkitEconomics together with the Chartered Institute of Procurement & Supply. The indicator shows the activity level of the construction sector

Overview with Chart & Report: Markit/CIPS Services Purchasing Managers Index shows the activity of purchasing managers in the services sector. It is calculated by the Markit agency and the Charted Institute of Procurement and

Monthly dataset of the United Kingdom Services PMI, including historical data, latest releases, and long-term trends from 2022-08-31 to 2025-11-30. Available for free download in CSV format.

The S&P Global/CIPS UK Services PMI Final is a monthly economic indicator that measures the performance of the UK services sector, based on surveys of purchasing managers.

In March 2025, the Composite Purchasing Managers Index (PMI) in the United Kingdom was 52, compared with 50.5 in the previous month. Following the COVID-19 outbreak, the composite PMI fell from 53 in February 2020, to 13.8 by April, highlighting the dire economic situation brought on by the pandemic. The composite PMI recovered from July onwards, but fell to 49 in November 2020, with a slight recovery in December preceding an even further drop to 41.2 in January 2021.

Overview with Chart & Report: Markit Composite PMI is a monthly summary report concerning the changes in the working conditions of private companies in the manufacturing and service sectors. The indicator calculation is based on

The S&P Global/CIPS UK Services PMI Final is a monthly economic indicator that measures the performance of the UK services sector, based on surveys of purchasing managers.-2023-03-03

View monthly updates and historical trends for UK Industrial Production Index: Manufacturing. from United Kingdom. Source: Office for National Statistics.…

Overview with Chart & Report: Markit/CIPS All Sector PMI is a monthly summary report concerning the changes in the working conditions of companies in all sectors of the economy. The indicator is calculated as a weighted average

This dataset provides values for CONSTRUCTION PMI reported in several countries. The data includes current values, previous releases, historical highs and record lows, release frequency, reported unit and currency.

The 'S&P Global Services PMI Flash' for the UK is an economic indicator that measures the activity level of purchasing managers in the services sector.-2025-03-24

The UK health and medical insurance market, valued at approximately £8.17 billion in 2025, is projected to experience robust growth, driven by several key factors. Rising healthcare costs, coupled with an aging population and increasing prevalence of chronic diseases, are placing significant pressure on the National Health Service (NHS). This is leading to a surge in demand for private medical insurance (PMI) among individuals and employers seeking faster access to specialist care and shorter waiting times. The market is segmented by product type (Private Medical Insurance – individual and group policies; Healthcare Cash Plans; Dental Insurance Plans) and procurement type (self-pay and employer-sponsored). The growth of employer-sponsored health coverage reflects a trend among businesses to offer competitive benefits packages to attract and retain talent. Furthermore, technological advancements, such as telehealth and digital health platforms, are improving accessibility and efficiency within the sector, fueling further market expansion. Competitive pressures from established players like Bupa, AXA PPP, and Aviva, alongside the emergence of newer entrants, are fostering innovation and driving down costs in specific segments. However, market growth is not without its restraints. Regulatory changes, economic uncertainties, and concerns over affordability, particularly for individual policies, pose challenges to the market's expansion. The increasing cost of premiums, alongside concerns about policy exclusions and limitations, can impact consumer adoption. Despite these challenges, the long-term outlook for the UK health and medical insurance market remains positive. The projected Compound Annual Growth Rate (CAGR) of 4.56% suggests a considerable increase in market value over the forecast period (2025-2033). This growth is likely to be driven primarily by the continued demand for private healthcare solutions, supplemented by ongoing technological advancements and an evolving regulatory landscape that shapes both competition and consumer access. Recent developments include: On November 2022, in partnership with online platform JAAQ in a six-month trial for boosting access to personalised expert-led health advice online. This adds to Bupa's mental health support which provides ongoing, around-the-clock support for a wealth of mental health conditions, such as anxiety, depression and addiction., On February 2022, AXA UK&I acquired renewable rights to Ageas UK's commercial business at an initial consideration of 47.5 million GBP. This acquisition will strengthen AXA's growth strategy and commitment to its commercial business customers and broker partnerships, particularly in the SME and Schemes market segments. As part of the agreement, around 100 Ageas UK employees will move to AXA Commercial to provide ongoing support and service delivery.. Notable trends are: Global Economic Slowdown and Better Government Insurance Services Affecting the United Kingdom Health and Medical Insurance.

The 'S&P Global Services PMI Flash' for the UK is an economic indicator that measures the activity level of purchasing managers in the services sector.-2025-11-21

IntroductionDespite the tobacco industry’s (TI) decades-long history of manipulating science, Philip Morris International (PMI) now frames itself as a benevolent funder of science and, in 2017, launched a new scientific organisation, the Foundation for a Smoke-Free World (FSFW). With concerns mounting that PMI’s actions are echoing historical TI influence on science, we aimed to understand the extent to which the public trusts PMI’s involvement in science, and whether channelling funds through a third-party organisation affects these levels of trust.MethodsThrough a representative survey of the UK public (n=1580) we investigated trust in direct (PMI), indirect (FSFW), and no (Cancer Research UK) TI involvement in science. Conservative worldview was investigated as a possible predictor of trust. Structural equation modelling was used to explore associations between variables.ResultsAlthough PMI was significantly less trusted than FSFW and Cancer Research UK, the public did not completely distrust it as a scientific source. Trust in FSFW’s involvement in science was higher before participants understood its TI funding. People with conservative worldviews demonstrated greater trust in TI involvement in science.DiscussionThe UK public needs to be better informed that the TI is not a trustworthy scientific source. Since channelling TI research funds through a third party increases the perceived trustworthiness of its science, steps to prevent such relationships are warranted. People with conservative leanings hold concerning views on TI involvement in science, which may be particularly hard to correct.

The slow but spontaneous and ubiquitous formation of C3(H2O), the hydrolytic and conformationally rearranged product of C3, initiates antibody-independent activation of the complement system that is a key first line of antimicrobial defense. The structure of C3(H2O) has not been determined. Here we subjected C3(H2O) to quantitative cross-linking/mass spectrometry (QCLMS). This revealed details of the structural differences and similarities between C3(H2O) and C3, as well as between C3(H2O) and its pivotal proteolytic cleavage product, C3b, which shares functionally similarity with C3(H2O). Considered in combination with the crystal structures of C3 and C3b, the QCMLS data suggest that C3(H2O) generation is accompanied by the migration of the thioester-containing domain of C3 from one end of the molecule to the other. This creates a stable C3b-like platform able to bind the zymogen, factor B, or the regulator, factor H. Integration of available crystallographic and QCLMS data allowed the determination of a 3D model of the C3(H2O) domain architecture. The unique arrangement of domains thus observed in C3(H2O), which retains the anaphylatoxin domain (that is excised when C3 is enzymatically activated to C3b), can be used to rationalize observed differences between C3(H2O) and C3b in terms of complement activation and regulation.

For more information about how to reproduce this modeling, see the Sali lab website or the README file.

Der Markit/CIPS Baugewerbe PMI wird von Markit zusammen mit dem Chartered Institute of Procurement & Supply veröffentlicht. Der Indikator misst den Aktivitätsgrad der Einkaufsmanager des Baugewerbes

The 'S&P Global Services PMI Flash' for the UK is an economic indicator that measures the activity level of purchasing managers in the services sector.-2025-12-16

UK Markit/CIPS Construction PMI est publié par MarkitEconomics en collaboration avec le Chartered Institute of Procurement & Supply. Lindicateur montre le niveau dactivité des directeurs des