Prior to 1829, the area of modern day Greece was largely under the control of the Ottoman Empire. In 1821, the Greeks declared their independence from the Ottomans, and achieved it within 8 years through the Greek War of Independence. The Independent Kingdom of Greece was established in 1829 and made up the southern half of present-day, mainland Greece, along with some Mediterranean islands. Over the next century, Greece's borders would expand and readjust drastically, through a number of conflicts and diplomatic agreements; therefore the population of Greece within those political borders** was much lower than the population in what would be today's borders. As there were large communities of ethnic Greeks living in neighboring countries during this time, particularly in Turkey, and the data presented here does not show the full extent of the First World War, Spanish Flu Pandemic and Greko-Turkish War on these Greek populations. While it is difficult to separate the fatalities from each of these events, it is estimated that between 500,000 and 900,000 ethnic Greeks died at the hands of the Ottomans between the years 1914 and 1923, and approximately 150,000 died due to the 1918 flu pandemic. These years also saw the exchange of up to one million Orthodox Christians from Turkey to Greece, and several hundred thousand Muslims from Greece to Turkey; this exchange is one reason why Greece's total population did not change drastically, despite the genocide, displacement and demographic upheaval of the 1910s and 1920s. Greece in WWII A new Hellenic Republic was established in 1924, which saw a decade of peace and modernization in Greece, however this was short lived. The Greek monarchy was reintroduced in 1935, and the prime minister, Ioannis Metaxas, headed a totalitarian government that remained in place until the Second World War. Metaxas tried to maintain Greek neutrality as the war began, however Italy's invasion of the Balkans made this impossible, and the Italian army tried invading Greece via Albania in 1940. The outnumbered and lesser-equipped Greek forces were able to hold off the Italian invasion and then push them backwards into Albania, marking the first Allied victory in the war. Following a series of Italian failures, Greece was eventually overrun when Hitler launched a German and Bulgarian invasion in April 1941, taking Athens within three weeks. Germany's involvement in Greece meant that Hitler's planned invasion of the Soviet Union was delayed, and Hitler cited this as the reason for it's failure (although most historians disagree with this). Over the course of the war approximately eight to eleven percent of the Greek population died due to fighting, extermination, starvation and disease; including over eighty percent of Greece's Jewish population in the Holocaust. Following the liberation of Greece in 1944, the country was then plunged into a civil war (the first major conflict of the Cold War), which lasted until 1949, and saw the British and American-supported government fight with Greek communists for control of the country. The government eventually defeated the Soviet-supported communist forces, and established American influence in the Aegean and Balkans throughout the Cold War. Post-war Greece From the 1950s until the 1970s, the Marshall Plan, industrialization and an emerging Tourism sector helped the Greek economy to boom, with one of the strongest growth rates in the world. Apart from the military coup, which ruled from 1967 to 1974, Greece remained relatively peaceful, prosperous and stable throughout the second half of the twentieth century. The population reached 11.2 million in the early 2000s, before going into decline for the past fifteen years. This decline came about due to a negative net migration rate and slowing birth rate, ultimately facilitated by the global financial crisis of 2007 and 2008; many Greeks left the country in search of work elsewhere, and the economic troubles have impacted the financial incentives that were previously available for families with many children. While the financial crisis was a global event, Greece was arguably the hardest-hit nation during the crisis, and suffered the longest recession of any advanced economy. The financial crisis has had a consequential impact on the Greek population, which has dropped by 800,000 in 15 years, and the average age has increased significantly, as thousands of young people migrate in search of employment.

Neolithic Greece mtDNA sequences

The 47 mitochondrial sequences generated for this work are available in the .arp format for the program ARLEQUIN (http://cmpg.unibe.ch/software/arlequin35/).

Simulated Data and Simulation Program

This dataset permits to simulate the scenarios investigated in the article submitted by Silva et al, using the modified version of the program SPLATCHE2 provided here (http://www.splatche.com).

There is a zipped folder Silva_et_al_SimulationSettings" that contains:

i) SPLATCHE2 executable called "SPLATCHE2-VariableAdmixture".

ii) a folder "DanubeRouteExpansion" including the settings used for the simulation of the four scenarios of the Neolithic expansion along the Danubian route.

iii) a folder "GreeceContinuity" including the settings used to perform the structured population continuity test.

A "ReadMe.txt" file is available in both settings folders with the instructions to launch the simulations.

The Kashmiri population is an ethno-linguistic group that resides in the Kashmir Valley in northern India. A longstanding hypothesis is that this population derives ancestry from Jewish and/or Greek sources. There is historical and archaeological evidence of ancient Greek presence in India and Kashmir. Further, some historical accounts suggest ancient Hebrew ancestry as well. To date, it has not been determined whether signatures of Greek or Jewish admixture can be detected in the Kashmiri population. Using genome-wide genotyping and admixture detection methods, we determined there are no significant or substantial signs of Greek or Jewish admixture in modern-day Kashmiris. The ancestry of Kashmiri Tibetans was also determined, which showed signs of admixture with populations from northern India and west Eurasia. These results contribute to our understanding of the existing population structure in northern India and its surrounding geographical areas.