*All rates are specified per day;#DAT = direct agglutination test;§LST = leishmanin skin test;A: Estimates as in [26] and documented in the Methods section.B: Ranges of uniform distributions used to randomly generating parameter combinations.C: Parameter combinations fulfilling the likelihood criterion as documented in the Methods section.D: For corresponding values of Re see Figure 2A at 12.5% sand fly reduction.

Model 1 assumes uncorrelated abundances. Model 2 assumes correlated abundances among species of the same foraging guild. Model 3 assumes correlated abundances among all species. Monte Carlo standard errors are given in parentheses.

Mathematical details of the computation of the means, variances, and covariance of the nonstationary Gompertz process.

aBased on the information given in the 2002 DNV report [45] and the 1999 Science Steering Committee report [47].

aHR was evaluated between higher and lower ALT categories.b“Up than median/below median ALT” represented comparison between population with ALT value higher than median level and population with ALT value below the median level (ALT level was continuous); “Highest/lowest ALT” represented comparison between population with ALT value in the highest category and population with ALT value in the lowest category (ALT level was incontinuous).cthe adjusted MetS components were defined by NCEP-ATP-III criteria [35]; “Yes” represented four or more MetS covariates adjusted; “No” represented less than four MetS covariates adjusted.d“No” represented the study not defined the “normal range” of ALT level or ≤95% of subjects were in the self-defined “normal range ” of ALT level; “Yes” represented the study defined the “normal range” of ALT level and >95% (or large part) of subjects were in the self-defined “normal range” of ALT level.Abbreviations: ALT: alanine aminotransferase; CI: confidence interval; CV: cardiovascular; HR: hazard ratio.