In 2024, there are six countries, all in Sub-Saharan Africa, where the average woman of childbearing age can expect to have around six or more children throughout their lifetime. In fact, of the 20 countries in the world with the highest fertility rates, Afghanistan is the only country not found in Sub-Saharan Africa. High fertility rates in Africa With a fertility rate of almost 7 children per woman, Niger is the country with the highest fertility rate in the world. Population growth in Niger is among the highest in the world. Lack of healthcare access, as well as food instability, political instability, and climate change, are all exacerbating conditions that keep Niger's infant mortality rates high, which is generally the driver behind high fertility rates. This situation is common across much of the continent, and, although there has been considerable progress in recent decades, development in Sub-Saharan Africa is not moving as quickly as it did in other less-developed regions. Demographic transition While these countries have the highest fertility rates in the world, their rates are all on a generally downward trajectory due to a phenomenon known as the demographic transition. The third stage (of four or five) of this transition sees birth rates drop in response to decreased infant and child mortality, as families no longer feel the need to compensate for lost children. Eventually, fertility rates fall below replacement level (approximately 2.1 children per woman), which eventually leads to natural population decline once life expectancy plateaus. In some of the most developed countries today, low fertility rates are

The statistic shows the 20 countries with the lowest fertility rates in 2024. All figures are estimates. In 2024, the fertility rate in Taiwan was estimated to be at 1.11 children per woman, making it the lowest fertility rate worldwide. Fertility rate The fertility rate is the average number of children born per woman of child-bearing age in a country. Usually, a woman aged between 15 and 45 is considered to be in her child-bearing years. The fertility rate of a country provides an insight into its economic state, as well as the level of health and education of its population. Developing countries usually have a higher fertility rate due to lack of access to birth control and contraception, and to women usually foregoing a higher education, or even any education at all, in favor of taking care of housework. Many families in poorer countries also need their children to help provide for the family by starting to work early and/or as caretakers for their parents in old age. In developed countries, fertility rates and birth rates are usually much lower, as birth control is easier to obtain and women often choose a career before becoming a mother. Additionally, if the number of women of child-bearing age declines, so does the fertility rate of a country. As can be seen above, countries like Hong Kong are a good example for women leaving the patriarchal structures and focusing on their own career instead of becoming a mother at a young age, causing a decline of the country’s fertility rate. A look at the fertility rate per woman worldwide by income group also shows that women with a low income tend to have more children than those with a high income. The United States are neither among the countries with the lowest, nor among those with the highest fertility rate, by the way. At 2.08 children per woman, the fertility rate in the US has been continuously slightly below the global average of about 2.4 children per woman over the last decade.

In 2023, the Faroe Islands was the European country estimated to have the highest fertility rate. The small Atlantic island state had a fertility rate of 2.71 children per woman. Other small countries such as Monaco and Gibraltar also came towards the top of the list for 2023, while the large country with the highest fertility rate was France, with 1.79 children per woman. On the other hand, Andorra, San Marino, and Malta had the lowest fertility rates in Europe, with Ukraine, Spain, and Italy being the largest countries with low fertility rates in that year, averaging around 1.3 children per woman.

Today, globally, women of childbearing age have an average of approximately 2.2 children over the course of their lifetime. In pre-industrial times, most women could expect to have somewhere between five and ten live births throughout their lifetime; however, the demographic transition then sees fertility rates fall significantly. Looking ahead, it is believed that the global fertility rate will fall below replacement level in the 2050s, which will eventually lead to population decline when life expectancy plateaus. Recent decades Between the 1950s and 1970s, the global fertility rate was roughly five children per woman - this was partly due to the post-WWII baby boom in many countries, on top of already-high rates in less-developed countries. The drop around 1960 can be attributed to China's "Great Leap Forward", where famine and disease in the world's most populous country saw the global fertility rate drop by roughly 0.5 children per woman. Between the 1970s and today, fertility rates fell consistently, although the rate of decline noticeably slowed as the baby boomer generation then began having their own children. Replacement level fertility Replacement level fertility, i.e. the number of children born per woman that a population needs for long-term stability, is approximately 2.1 children per woman. Populations may continue to grow naturally despite below-replacement level fertility, due to reduced mortality and increased life expectancy, however, these will plateau with time and then population decline will occur. It is believed that the global fertility rate will drop below replacement level in the mid-2050s, although improvements in healthcare and living standards will see population growth continue into the 2080s when the global population will then start falling.

The result of ECM modelling.

Chart and table of the Costa Rica fertility rate from 1950 to 2025. United Nations projections are also included through the year 2100.

Between 2010 and 2023, the fertility rate in Sweden decreased steadily, dropping to 1.5. The fertility rate is defined as the number of children that would be born or are likely to be born to a woman if she lives to the end of her reproductive years. A similar decline was visible for the crude birth rate, which in 2022 was down at 10 births per 1,000 inhabitants.

More immigrants than emigrants

Despite the decreasing fertility- and crude birth rate in Sweden, the population in Sweden continues to grow. More babies are born each year than people dying, which contributes to a growing population. However, the major reason behind the continued population growth is the positive inflow of immigrants. Few people are leaving the country, while many more migrants are arriving in Sweden.

Fertility rate in Europe

Even though the fertility rate in the country decreased over the last 10 years, Sweden had a higher fertility rate than many other countries in Europe in 2023. The Faroe Islands had the highest fertility rate, whereas Andorra had the lowest.

With an average of 4.3 births per woman, Afghanistan had the highest fertility rate throughout the Asia-Pacific region in 2024. Pakistan and Papua New Guinea followed with the second and third-highest fertility rates, respectively. In contrast, South Korea and Hong Kong had the lowest fertility rates across the region. Contraception usage Fertility rates among women in the Asia-Pacific region have fallen throughout recent years. A likely reason is an increase in contraception use. However, contraception usage varies greatly throughout the Asia-Pacific region. Although contraception prevalence is set to increase across South Asia by 2030, women in both East Asia and Southeast Asia had higher contraception usage compared to South Asia in 2019. Women in APAC With the rise of feminism and the advancement of human rights, attitudes towards the role of women have changed in the Asia-Pacific region. Achieving gender equality has become a vital necessity for both men and women throughout the region. Alongside changes in traditional gender roles, women in certain Asia-Pacific countries, such as New Zealand, have become more inclined to marry later in life. Furthermore, the focus for younger women appears to be with having stability in their lives and securing an enjoyable job. This was displayed when female high school students in Japan were questioned about their future life aspirations.

Chart and table of the Honduras fertility rate from 1950 to 2025. United Nations projections are also included through the year 2100.

Follicular regulatory T cells (Tfr) can play opposite roles in the regulation of germinal center (GC) responses. Depending on the studies, Tfr suppress or support GCs and B cell affinity maturation. However, which factors determine positive versus negative effects of Tfr on the GC B cells is unclear. In this study we show that GC centrocytes that express MYC upregulate expression of CCL3 chemokine that is essential for both the positive and negative regulation of GC B cells by Tfr. B cell intrinsic expression of CCL3 contributes to Tfr-dependent positive selection of foreign Ag-specific GC B cells. At the same time, expression of CCL3 is critical for direct Tfr-mediated suppression of GC B cells that acquire cognate to Tfr nuclear proteins. Our study suggests that CCR5 and CCR1 receptors promote Tfr migration to CCL3 and highlights Ccr5 expression on Tfr subset that expresses Il10. Based on our findings and previous studies, we suggest a model of chemotactically-targeted checkpoint cont..., All flow data were collect based on the following procedures. Single-cell suspensions from draining lymph nodes and spleens were prepared and filtered through a 70-µm nylon cell strainer (BD). Red blood cells were lysed. Cells were washed in FACS buffer (2% FBS, 1mM EDTA, 0.1% NaN3 in PBS) and followed by surface staining for the indicated markers for 20 min at 4℃. For intracellular staining, after surface markers were stained, cells were fixed and stained by using regulatory T cell Staining Buffer Set (Thermo Fisher Scientific) according to the manufacturer’s instructions. All samples were acquired on a BD FACSCanto flow cytometer. For cell sorting, enriched B cells and T cells were incubated with antibodies in Sorting buffer (0.5% FBS and 2 mM EDTA in PBS) and were performed on a BD FACSAria III cell sorter. All flow data were analyzed with FlowJo (version 10.6.0) software. VH186.2 sequence analysis of GC B cells based on the following protocol. Genomic DNA was extracted using QIAam..., , # Targeted checkpoint control of B cells undergoing positive selection in germinal centers by follicular regulatory T cells

This dataset includes all the flow cytometry and VH186.2 sequence analysis of GC B cells raw data. These original data are the sources of the results of our paper. Our results show that GC centrocytes that express MYC upregulate expression of CCL3 chemokine that is essential for both the positive and negative regulation of GC B cells by Tfr. B cell intrinsic expression of CCL3 contributes to Tregs-dependent positive selection of foreign Ag-specific GC B cells. At the same time, expression of CCL3 is critical for direct Tfr-mediated suppression of GC B cells that acquire cognate to Tfr nuclear proteins.

Description of the Data and file structure

This dataset is organized by different experimental contexts.

Original Data

|_ Flow Cytometry Data/

| |_ Bone Marrow Chimeras immunized with SA-NucPr and SA/

| |_ CCL3 WT and CCL3 KO Bone Marrow chimeras ...

Niger had the highest birth rate in the world in 2024, with a birth rate of 46.6 births per 1,000 inhabitants. Angola, Benin, Mali, and Uganda followed. Except for Afghanistan, all the 20 countries with the highest birth rates in the world were located in Sub-Saharan Africa. High infant mortality The reasons behind the high birth rates in many Sub-Saharan African countries are manyfold, but a major reason is that infant mortality remains high on the continent, despite decreasing steadily over the past decades, resulting in high birth rates to counter death rates. Moreover, many nations in Sub-Saharan Africa are highly reliant on small-scale farming, meaning that more hands are of importance. Additionally, polygamy is not uncommon in the region, and having many children is often seen as a symbol of status. Fastest growing populations As the high fertility rates coincide with decreasing death rates, countries in Sub-Saharan Africa have the highest population growth rates in the world. As a result, with Africa's population forecast to increase from 1.4 billion in 2022 to over 3.9 billion by 2100.

The fertility rate of a country is the average number of children that women from that country will have throughout their reproductive years. From 1800 until 1865, Japan's fertility rate grew quite gradually, from 4.1 children per woman, to 4.8. From this point the fertility rate drops to 3.6 over the next ten years, as Japan became more industrialized. Towards the end of the nineteenth century, Japan's fertility rate grew again, and reached it's highest recorded point in the early 1920s, where it was 5.4 children per woman. Since this point it has been gradually decreasing until now, although it did experience slight increases after the Second World War, and in the early 1970s. In recent decades Japan's population has aged extensively, and today, Japan has the second oldest population and second highest life expectancy in the world (after Monaco). In contrast to this, Japan has a very low birth rate, and it's fertility rate is expected to fall below 1.4 children per woman in 2020.

transferrin receptor Enables several functions, including double-stranded RNA binding activity; protein homodimerization activity; and transferrin receptor activity. Involved in several processes, including multicellular organismal-level iron ion homeostasis; negative regulation of mitochondrial fusion; and positive regulation of lymphocyte activation. Acts upstream of or within cellular response to xenobiotic stimulus. Located in several cellular components, including basolateral plasma membrane; clathrin-coated pit; and endosome. Part of HFE-transferrin receptor complex. Is active in plasma membrane. Implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian cancer. Biomarker of breast cancer; carcinoma (multiple); iron deficiency anemia; and prostate cancer. This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

In 2021, the total fertility rate (TFR) in Okinawa Prefecture amounted to 1.8, the highest among the 47 prefectures of Japan. By comparison, Tokyo prefecture recorded the lowest fertility rate of 1.08. That year, the overall total fertility rate in the country stood at 1.3.

For most of the past two centuries, falling birth rates have been associated with societal progress. During the demographic transition, where pre-industrial societies modernize in terms of fertility and mortality, falling death rates, especially among infants and children, are the first major change. In response, as more children survive into adulthood, women have fewer children as the need to compensate for child mortality declines. This transition has happened at different times across the world and is an ongoing process, with early industrial countries being the first to transition, and Sub-Saharan African countries being the most recent to do so. Additionally, some Asian countries (particularly China through government policy) have gone through their demographic transitions at a much faster pace than those deemed more developed. Today, in countries such as Japan, Italy, and Germany, birth rates have fallen well below death rates; this is no longer considered a positive demographic trend, as it leads to natural population decline, and may create an over-aged population that could place a burden on healthcare systems.

In 2022, the total fertility rate in India remained nearly unchanged at around 2.01 children per woman. Yet 2022 saw the lowest fertility rate in India with 2.01 children per woman. The total fertility rate is the average number of children that a woman of childbearing age (generally considered 15 to 44 years) is expected to have throughout her reproductive years. Unlike birth rates, which are based on the actual number of live births in a given population, fertility rates are estimates (similar to life expectancy) that apply to a hypothetical woman, as they assume that current patterns in age-specific fertility will remain constant throughout her reproductive years.Find more statistics on other topics about India with key insights such as life expectancy of men at birth, death rate, and life expectancy of women at birth.

Abstract

The importance of administrative statistics is much worth as it offers a good opportunity to get data at a cheaper cost compared to censuses and sample surveys. Administrative statistics are also very essential to calculate some important demographic measures for instance health administrative statistics such as crude birth rate, general fertility rate, age specific fertility rate, total fertility rate, gross reproduction rate, net reproduction rate, crude death rates, marriage and divorce rates, etc., under the condition that they are complete and accurate.

Geographic coverage

National coverage

Analysis unit

The development of Health Administrative Data Progress Assessment focused on women and children as units of analysis.

Universe

This assessment targeted women and children

Kind of data

Administrative records data [adm]

Mode of data collection

Other [oth]

Cleaning operations

For the calculation of fertility indicators, two sources of administrative statistics( HMIS and CRVS) were used.

The Health Management Information System (HMIS) has collected the aggregated number of births in 2015 and 2016. For the corresponding years, the Civil Registration and Vital Statistics system (CRVS) has collected the number of births by the age of their mothers at the time of birth. To calculate fertility indicators like ASFR, TFR, and GRR, we need the number of births tabulated according to age of their mothers at birth.

Since the number of births registered in HMIS is close to expectation vis-à-vis the expected annual birth, fertility indicators were computed using HMIS data and these data have been imputed following the births distribution by age of the mothers (15-49) from the CRVS assuming that the same distribution of births according to the age of their mothers applies.

Data appraisal

A combination of sources of data namely Health Management Information System (HMIS) and Civil Registration and Vital Statistics web based application (CRVS) is very useful for quality data. The 4th Rwanda Population and Housing Census conducted in 2012 and Rwanda Demographic and Health Survey (RDHS) conducted in 2014/15 were also used to benchmark on expectations and achievements for now.

Abstract

The 2008 Sierra Leone Demographic and Health Survey (SLDHS) is the first DHS survey to be held in Sierra Leone. Teams visited 353 sample points across Sierra Leone and collected data from a nationally representative sample of 7,374 women age 15-49 and 3,280 men age 15-59. The primary purpose of the 2008 SLDHS is to provide policy-makers and planners with detailed information on Demography and health.

This is the first Demographic and Health Survey conducted in Sierra Leone and was carried out by Statistics Sierra Leone (SSL) in collaboration with the Ministry of Health and Sanitation. The 2008 SLDHS was funded by the Sierra Leone government, UNFPA, UNDP, UNICEF, DFID, USAID, and The World Bank. WHO, WFP and UNHCR provided logistical support. ICF Macro, an ICF International Company, provided technical support for the survey through the MEASURE DHS project. MEASURE DHS is sponsored by the United States Agency for International Development (USAID) to assist countries worldwide in obtaining information on key population and health indicators.

The purpose of the SLDHS is to collect national- and regional-level data on fertility and contraceptive use, marriage and sexual activity, fertility preferences, breastfeeding practices, nutritional status of women and young children, childhood and adult mortality, maternal and child health, female genital cutting, awareness and behaviour regarding HIV/AIDS and other sexually transmitted infections, adult health, and other issues. The survey obtained detailed information on these topics from women of reproductive age and, for certain topics, from men as well. The 2008 SLDHS was carried out from late April 2008 to late June 2008, using a nationally representative sample of 7,758 households.

The survey results are intended to assist policymakers and planners in assessing the current health and population programmes and in designing new strategies for improving reproductive health and health services in Sierra Leone.

MAIN RESULTS

FERTILITY

Survey results indicate that there has been little or no decline in the total fertility rate over the past two decades, from 5.7 children per woman in 1980-85 to 5.1 children per woman for the three years preceding the 2008 SLDHS (approximately 2004-07). Fertility is lower in urban areas than in rural areas (3.8 and 5.8 children per woman, respectively). Regional variations in fertility are marked, ranging from 3.4 births per woman in the Western Region (where the capital, Freetown, is located) to almost six births per woman in the Northern and Eastern regions. Women with no education give birth to almost twice as many children as women who have been to secondary school (5.8 births, compared with 3.1 births). Fertility is also closely associated with household wealth, ranging from 3.2 births among women in the highest wealth quintile to 6.3 births among women in the lowest wealth quintile, a difference of more than three births. Research has demonstrated that children born too close to a previous birth are at increased risk of dying. In Sierra Leone, only 18 percent of births occur within 24 months of a previous birth. The interval between births is relatively long; the median interval is 36 months.

FAMILY PLANNING

The vast majority of Sierra Leonean women and men know of at least one method of contraception. Contraceptive pills and injectables are known to about 60 percent of currently married women and 49 percent of married men. Male condoms are known to 58 percent of married women and 80 percent of men. A higher proportion of respondents reported knowing a modern method of family planning than a traditional method.

About one in five (21 percent) currently married women has used a contraceptive method at some time-19 percent have used a modern method and 6 percent have used a traditional method. However, only about one in twelve currently married women (8 percent) is currently using a contraceptive method. Modern methods account for almost all contraceptive use, with 7 percent of married women reporting use of a modern method, compared with only 1 percent using a traditional method. Injectables and the pill are the most widely used methods (3 and 2 percent of married women, respectively), followed by LAM and male condoms (less than 1 percent each).

CHILD HEALTH

Examination of levels of infant and child mortality is essential for assessing population and health policies and programmes. Infant and child mortality rates are also used as indices reflecting levels of poverty and deprivation in a population. The 2008 survey data show that over the past 15 years, infant and under-five mortality have decreased by 26 percent. Still, one in seven Sierra Leonean children dies before reaching age five. For the most recent five-year period before the survey (approximately calendar years 2003 to 2008), the infant mortality rate was 89 deaths per 1,000 live births and the under-five mortality rate was 140 deaths per 1,000 live births. The neonatal mortality rate was 36 deaths per 1,000 live births and the post-neonatal mortality rate was 53 deaths per 1,000 live births. The child mortality rate was 56 deaths per 1,000 children surviving to age one year. Mortality rates at all ages of childhood show a strong relationship with the length of the preceding birth interval. Under-five mortality is three times higher among children born less than two years after a preceding sibling (252 deaths per 1,000 births) than among children born four or more years after a previous child (deaths 81 per 1,000 births).

MATERNAL HEALTH

Almost nine in ten mothers (87 percent) in Sierra Leone receive antenatal care from a health professional (doctor, nurse, midwife, or MCH aid). Only 5 percent of mothers receive antenatal care from a traditional midwife or a community health worker; 7 percent of mothers do not receive any antenatal care.

In Sierra Leone, over half of mothers have four or more antenatal care (ANC) visits, about 20 percent have one to three ANC visits, and only 7 percent have no antenatal care at all. The survey shows that not all women in Sierra Leone receive antenatal care services early in pregnancy. Only 30 percent of mothers obtain antenatal care in the first three months of pregnancy, 41 percent make their first visit in the fourth or fifth month, and 17 percent in have their first visit in the sixth or seventh month. Only 1 percent of women have their first ANC visit in their eighth month of pregnancy or later.

BREASTFEEDING AND NUTRITION

Poor nutritional status is one of the most important health and welfare problems facing Sierra Leone today and particularly afflicts women and children. The data show that 36 percent of children under five are stunted (too short for their age) and 10 percent of children under five are wasted (too thin for their height). Overall, 21 percent of children are underweight, which may reflect stunting, wasting, or both. For women, at the national level 11 percent of women are considered to be thin (body mass index <18.5); however, only 4 percent of women are considered severely thin. At the other end of a spectrum, 20 percent of women age 15-49 are considered to be overweight (body mass index 25.025.9) and 9 percent are considered obese (body mass index =30.0).

HIV/AIDS

The HIV/AIDS pandemic is one of the most serious health concerns in the world today because of its high case-fatality rate and the lack of a cure. Awareness of AIDS is relatively high among Sierra Leonean adults age 15-49, with 69 percent of women and 83 percent of men saying that they have heard about AIDS. Nevertheless, only 14 percent of women and 25 percent of men are classified as having 'comprehensive knowledge' about AIDS, i.e., knowing that consistent use of condoms during sexual intercourse and having just one faithful, HIV-negative partner can reduce the chances of getting HIV/AIDS, knowing that a healthy-looking person can have HIV (the virus that causes AIDS), and knowing that HIV cannot be transmitted by sharing food/utensils with someone who has HIV/AIDS, or by mosquito bites.

Such a low level of knowledge about HIV/AIDS implies that a concerted effort is needed to address misconceptions about the transmission of HIV in Sierra Leone. Comprehensive knowledge is substantially lower among respondents with no education and those who live in the poorest households. Programmes could be targeted to populations in rural areas, and especially women in the Northern and Southern regions and men in the Eastern Region, where comprehensive knowledge is lowest. A composite indicator on stigma towards people who are HIV positive shows that only 5 percent of women and 15 percent of men age 15-49 expressed accepting attitudes towards persons living with HIV/AIDS.

FEMALE CIRCUMCISION

The 2008 SLDHS collected data on the practice of female circumcision (or female genital cutting) in Sierra Leone. Awareness of the practice is universally high. Almost all (99 percent) of Sierra Leonean women and 96 percent of men age 15-49 have heard of the practice. The prevalence of female circumcision is high (91 percent). Most women (82 percent) reported that the cutting involves the removal of flesh. The most radical procedure, infibulation-when vagina is sewn closed during the circumcision-is reported by only 3 percent of women. The survey results indicate that almost all of the women were circumcised by traditional practitioners (95 percent); only a small proportion of circumcisions were performed by a trained health professional (0.3 percent).

Among Sierra Leonean adults age 15-49 who have heard of female circumcision, more men than women oppose the practice (41 and 26 percent, respectively), which is similar to patterns in other West African countries.

Geographic coverage

The survey used a

The fertility rates have fallen in all five Nordic countries over the last years. However, in 2021, the birth rates increased again in all five Nordics countries, besides in Sweden, where the fertility rate stayed the same. This can be explained by the higher number of babies born during the COVID-19 pandemic. In 2022, Iceland had the highest fertility rate of the Nordic countries, with 1.6 children born per woman in reproductive age. The global trend of decreasing fertility The Nordics are not the only region with decreasing fertility rates. Globally, fertility rates have been on a steady decline since 2000. While lower-income countries have had more significant declines, they still have more children born per woman than higher-income countries. In 2000, almost 6 children were born per woman in low-income countries, decreasing to 4.62 in 2021. By comparison, nearly 1.71 children were born per woman in high-income countries, falling slightly to 1.55 by 2021. Overall, in 2023, Niger, Angola, and the Democratic Republic of Congo had the highest fertility rates, while Taiwan, South Korea, and Singapore had the lowest fertility rates. Impacts of low fertility Greater access to education, challenges between work-life balance, and the costs of raising children can all be linked to falling fertility rates. However, this decline is not without consequences, and many countries are facing social and economic challenges because of aging and shrinking populations. For example, in Japan, where nearly 30 percent of the country is aged 65 or older, an increasing proportion of the government expenditure is going towards social security benefits. Moreover, the very low unemployment rate in Japan can partially be attributed to having a shrinking labor force and fewer people to support the economy.

The total fertility rate in Indonesia saw no significant changes in 2022 in comparison to the previous year 2021 and remained at around 2.15 children per woman. Yet 2022 saw the lowest fertility rate in Indonesia with 2.15 children per woman. The total fertility rate is the average number of children that a woman of childbearing age (generally considered 15 to 44 years) can hypothetically expect to have throughout her reproductive years. As fertility rates are estimates (similar to life expectancy), they refer to a hypothetical woman or cohort, and estimates assume that current age-specific fertility trends would remain constant throughout this person's reproductive years.Find more statistics on other topics about Indonesia with key insights such as fertility rate of women aged between 15 and 19 years old, female smoking rate, and infant mortality rate.