Graph and download economic data for ICE BofA Single-B US High Yield Index Effective Yield (BAMLH0A2HYBEY) from 1996-12-31 to 2025-08-28 about B Bond Rating, yield, interest rate, interest, rate, and USA.

Graph and download economic data for ICE BofA Single-B US High Yield Index Semi-Annual Yield to Worst (BAMLH0A2HYBSYTW) from 1996-12-31 to 2025-08-28 about YTW, yield, interest rate, interest, rate, and USA.

United States - ICE BofA Single-B US High Yield Index Effective Yield was 6.45% in August of 2025, according to the United States Federal Reserve. Historically, United States - ICE BofA Single-B US High Yield Index Effective Yield reached a record high of 23.07 in November of 2008 and a record low of 4.36 in June of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for United States - ICE BofA Single-B US High Yield Index Effective Yield - last updated from the United States Federal Reserve on September of 2025.

Graph and download economic data for ICE BofA BB US High Yield Index Option-Adjusted Spread (BAMLH0A1HYBB) from 1996-12-31 to 2025-08-28 about BB, option-adjusted spread, yield, interest rate, interest, rate, and USA.

United States - ICE BofA Single-B US High Yield Index Semi-Annual Yield to Worst was 6.75% in August of 2025, according to the United States Federal Reserve. Historically, United States - ICE BofA Single-B US High Yield Index Semi-Annual Yield to Worst reached a record high of 23.07 in November of 2008 and a record low of 4.15 in June of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for United States - ICE BofA Single-B US High Yield Index Semi-Annual Yield to Worst - last updated from the United States Federal Reserve on September of 2025.

United States - ICE BofA Single-B US High Yield Index Option-Adjusted Spread was 3.10% in August of 2025, according to the United States Federal Reserve. Historically, United States - ICE BofA Single-B US High Yield Index Option-Adjusted Spread reached a record high of 20.84 in November of 2008 and a record low of 2.36 in June of 2007. Trading Economics provides the current actual value, an historical data chart and related indicators for United States - ICE BofA Single-B US High Yield Index Option-Adjusted Spread - last updated from the United States Federal Reserve on August of 2025.

Graph and download economic data for ICE BofA Single-B US High Yield Index Total Return Index Value (BAMLHYH0A2BTRIV) from 1996-12-31 to 2025-08-28 about B Bond Rating, return, yield, interest rate, interest, rate, indexes, and USA.

ICE BofA Single-B US High Yield Index Yield - Historical chart and current data through 2025.

View data of the effective yield of an index of non-investment grade publically issued corporate debt in the U.S.

United States - ICE BofA Single-B US High Yield Total Return Value was 493.71000 Index in August of 2025, according to the United States Federal Reserve. Historically, United States - ICE BofA Single-B US High Yield Total Return Value reached a record high of 493.71000 in August of 2025 and a record low of 99.87000 in January of 1997. Trading Economics provides the current actual value, an historical data chart and related indicators for United States - ICE BofA Single-B US High Yield Total Return Value - last updated from the United States Federal Reserve on September of 2025.

Graph and download economic data for ICE BofA Euro High Yield Index Effective Yield (BAMLHE00EHYIEY) from 1997-12-31 to 2025-08-28 about Euro Area, Europe, yield, interest rate, interest, rate, and indexes.

Graph and download economic data for ICE BofA CCC & Lower US High Yield Index Option-Adjusted Spread (BAMLH0A3HYC) from 1996-12-31 to 2025-08-28 about CCC, option-adjusted spread, yield, interest rate, interest, rate, and USA.

Graph and download economic data for ICE BofA CCC & Lower US High Yield Index Effective Yield (BAMLH0A3HYCEY) from 1996-12-31 to 2025-08-31 about CCC, yield, interest rate, interest, rate, and USA.

United States - ICE BofA BB US High Yield Index Effective Yield was 5.47% in August of 2025, according to the United States Federal Reserve. Historically, United States - ICE BofA BB US High Yield Index Effective Yield reached a record high of 16.41 in December of 2008 and a record low of 3.01 in September of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for United States - ICE BofA BB US High Yield Index Effective Yield - last updated from the United States Federal Reserve on September of 2025.

Graph and download economic data for ICE BofA Euro High Yield Index Option-Adjusted Spread (BAMLHE00EHYIOAS) from 1997-12-31 to 2025-08-28 about option-adjusted spread, Euro Area, Europe, yield, interest rate, interest, rate, and indexes.

Graph and download economic data for ICE BofA Single-A US Corporate Index Effective Yield (BAMLC0A3CAEY) from 1996-12-31 to 2025-09-01 about A Bond Rating, yield, corporate, interest rate, interest, rate, and USA.

Graph and download economic data for ICE BofA BB US High Yield Index Semi-Annual Yield to Worst (BAMLH0A1HYBBSYTW) from 1996-12-31 to 2025-08-28 about YTW, BB, yield, interest rate, interest, rate, and USA.

The yield on US 30 Year Bond Yield eased to 4.95% on September 2, 2025, marking a 0.01 percentage point decrease from the previous session. Over the past month, the yield has edged up by 0.16 points and is 0.83 points higher than a year ago, according to over-the-counter interbank yield quotes for this government bond maturity. United States 30 Year Bond Yield - values, historical data, forecasts and news - updated on September of 2025.

The yield on US 10 Year Note Bond Yield rose to 4.23% on August 29, 2025, marking a 0.02 percentage point increase from the previous session. Over the past month, the yield has fallen by 0.15 points, though it remains 0.33 points higher than a year ago, according to over-the-counter interbank yield quotes for this government bond maturity. US 10 Year Treasury Bond Note Yield - values, historical data, forecasts and news - updated on September of 2025.

Influenza B virus (IBV) strains are one of the components of seasonal influenza vaccines in both trivalent and quadrivalent formulations. The vast majority of these vaccines are produced in embryonated chickens' eggs. While optimized backbones for vaccine production in eggs exist and are in use for influenza A viruses, no such backbones exist for IBVs, resulting in unpredictable production yields. To generate an optimal vaccine seed virus backbone, we have compiled a panel of 71 IBV strains from 1940 to present day, representing the known temporal and genetic variability of IBV circulating in humans. This panel contains strains from the B/Victoria/2/87-like lineage, B/Yamagata/16/88-like lineage and the ancestral lineage that preceded their split to provide a diverse set that would help to identify a suitable backbone which can be used in combination with hemagglutinin (HA) and neuraminidase (NA) glycoproteins from any IBV strain to be incorporated into the seasonal vaccine. We have characterized and ranked the growth profiles of the 71 IBV strains and the best performing strains were used for co-infection of eggs, followed by serial passaging to select for high-growth reassortant viruses. After serial passaging, we selected 10 clonal isolates based on their growth profiles assessed by hemagglutination and plaque-forming units. We then generated reverse genetics systems for the three clones that performed best in growth curves. The selected backbones were then used to generate different reassortant viruses with HA/NA combinations from high and low titer yielding wild type IBV. When the growth profiles of the recombinant reassortant viruses were tested, the low titer yielding HA/NA viruses with the selected backbones yielded higher titers similar to those from high titer yielding HA/NA combinations. The use of these IBV backbones with improved replication in eggs might increase yields for the influenza B virus components of seasonal influenza virus vaccines.