In 2022, the New Orleans-Metairie, LA metro area recorded the highest homicide rate of U.S. cities with a population over 250,000, at 27.1 homicides per 100,000 residents, followed by the Memphis, TN-MS-AR metro area. However, homicide data was not recorded in all U.S. metro areas, meaning that there may be some cities with a higher homicide rate.

St. Louis

St. Louis, which had a murder and nonnegligent manslaughter rate of 11.6 in 2022, is the second-largest city by population in Missouri. It is home to many famous treasures such as the St. Louis Cardinals baseball team, Washington University in St. Louis, the Saint Louis Zoo, and the renowned Gateway Arch. It is home to many corporations such as Monsanto, Arch Coal, and Emerson Electric. The economy of St. Louis is centered around business and healthcare, and in addition is home to ten Fortune 500 companies.

Crime in St. Louis

Despite all of this, St. Louis suffers from high levels of crime and violence. As of 2023, it was listed as the seventh most dangerous city in the world as a result of their extremely high murder rate. Not only does St. Louis have one of the highest homicide rates in the United States, it also reports one of the highest numbers of violent crimes. In spite of high crime levels, the GDP of the St. Louis metropolitan area has been increasing since 2001.

In 2023, around 3,640.56 violent crimes per 100,000 residents were reported in Oakland, California. This made Oakland the most dangerous city in the United States in that year. Four categories of violent crimes were used: murder and non-negligent manslaughter; forcible rape; robbery; and aggravated assault. Only cities with a population of at least 200,000 were considered.

In 2024, Colima in Mexico ranked as the world's most dangerous city with a homicide rate of 140 per 100,000 inhabitants. Seven of the 10 cities with the highest murder rates worldwide are all found in Mexico. The list does not include countries where war and conflict exist. Latin America dominate murder statistics Except for Mandela Bay, all the cities on the list are found in Latin America. Latin America also dominate the list of the world's most dangerous countries. Violence in Latin America is caused in great part by drug trafficking, weapons trafficking, and gang wars. Crime in South Africa Mandela Bay in South Africa is the only city outside Latin America among the 10 most dangerous cities worldwide. The country is struggling with extremely high levels of inequality, and is struggling with high levels of crime and power outages, harming the country's economy and driving more people into unemployment and poverty.