In 2024, Japan reported 16.4 suicides per 100,000 inhabitants. The country's suicide rate resumed its downward trend after an unexpected surge in recent years, likely connected to the COVID-19 pandemic. What are the reasons behind Japan’s high suicide rates?  While the majority of suicides in Japan stemmed from health reasons, existential concerns and problems directly related to work also accounted for thousands of self-inflicted deaths in the past years. One of the most profound issues faced by employees in Japan leading to self-harm is exhaustion. “Karoshi,” or death by overwork, is a well-known phenomenon in Japanese society. In addition to physical fatigue, karoshi may be precipitated by mental stress resulting from employment. Occupational stress or overwork-induced suicide is referred to as “karojisatsu (overwork suicide)” in Japan. Which demographic groups are affected? Although *************** are frequently depicted as the most at-risk demographic for suicide in Japan, the increasing occurrence of suicides among the elderly people and schoolchildren is causing concern. Bullying, isolation, and the lack of a proficient mental healthcare system can be additional factors contributing to the country’s high suicide rates among all age groups.