The mortality rate from influenza in the United States is by far highest among those aged 65 years and older. During the 2023-2024 flu season, the mortality rate from influenza for this age group was around 32.1 per 100,000 population. The burden of influenza The impact of influenza in the U.S. varies from season to season, but in the 2023-2024 flu season, there were an estimated 40 million cases. These cases resulted in around 470,000 hospitalizations. Although most people recover from influenza without requiring medical treatment, the disease can be deadly for young children, the elderly, and those with weakened immune systems or chronic illnesses. During the 2023-2024 flu season, around 28,000 people in the U.S. lost their lives due to influenza. Impact of vaccinations The most effective way to prevent influenza is to receive an annual vaccination at the beginning of flu season. Flu vaccines are safe and can greatly reduce the burden of the disease. During the 2022-2023 flu season, vaccinations prevented around 2,479 deaths among those aged 65 years and older. Although flu vaccines are usually cheap and easily accessible, every year a large share of the population in the U.S. still does not get vaccinated. For example, during the 2022-2023 flu season, only about 35 percent of those aged 18 to 49 years received a flu vaccination.

In 2021, there were **** death cases caused by the influenza virus in China. The death rate of the virus amounted to approximately ****** out of ten million people. Influenza, commonly known as "flu", is a highly contagious respiratory disease caused by influenza A or B viruses and can be prevented by vaccines. It should be noted that the Chinese health authorities calculate death cases for infectious diseases differently, counting only patients who died directly from the infectious disease.

The graph illustrates the number of flu-related deaths in the United States for each flu season from 2010-2011 to 2023-2024*. The x-axis represents the flu seasons, labeled from '10-11 to '23*-24*, while the y-axis shows the annual number of flu deaths. Throughout this period, flu deaths vary significantly, ranging from a low of 4,900 in the 2021-2022* season to a high of 51,000 in both the 2014-2015 and 2017-2018 seasons. Other notable figures include 36,000 deaths in 2010-2011, 42,000 in 2012-2013, and a recent increase to 28,000 in the 2023*-2024* season. The data exhibits considerable fluctuations with no consistent upward or downward trend, highlighting the variability in flu mortality rates over the years. This information is presented in a line graph format, effectively showcasing the yearly changes and peaks in flu-related deaths across the United States.

*Data for the 2021-2022 and 2022-2023 seasons are estimated.

The burden of influenza in the United States can vary from year to year depending on which viruses are circulating, how many people receive an influenza vaccination, and how effective the vaccination is in that particular year. During the 2023-2024 flu season, around 28,000 people lost their lives to the disease. Although most people recover from influenza without needing medical care, the disease can be deadly among young children, the elderly, and those with weakened immune systems or chronic illnesses. Deaths due to influenza Even though most people recover from influenza without medical care, influenza and pneumonia can be deadly, especially for older people and those with certain preexisting conditions. Influenza is a common cause of pneumonia and although most cases of influenza do not develop into pneumonia, those that do are often more severe and more deadly. Deaths due to influenza are most common among the elderly, with a mortality rate of around 32 per 100,000 population during the 2023-2024 flu season. In comparison, the mortality rate for those aged 50 to 64 years was 9.1 per 100,000 population. Flu vaccinations The most effective way to prevent influenza is to receive an annual influenza vaccination. These vaccines have proven to be safe and are usually cheap and easily accessible. Nevertheless, every year a large share of the population in the United States still fails to get vaccinated against influenza. For example, in the 2022-2023 flu season, only 35 percent of those aged 18 to 49 years received a flu vaccination. Unsurprisingly, children and the elderly are the most likely to get vaccinated. It is estimated that during the 2022-2023 flu season, vaccinations prevented over 929 thousand influenza cases among children aged 6 months to 4 years.

Following the outbreak of the H1N1 influenza pandemic of 1918, which came to be known as the Spanish Flu, the number of deaths due to influenza and pneumonia soared. Pneumonia was caused either by the influenza or by a bacterial superinfection that took hold due to the patient's weakened state as a result of the influenza, for this reason, influenza deaths and pneumonia deaths were recorded together as one. Pennsylvania had the highest mortality rate due to the pandemic, where there were over 880 fatalities per 100,000 people; meaning that approximately 0.9 percent of the state's population died from the Spanish Flu pandemic in 1918.

When compared with the 1915 mortality rates, many states, such as California and Pennsylvania, saw their mortality rate due to influenza and pneumonia increase five-fold by 1818, which was the worst year of the pandemic. While the mortality rate decreased significantly in the year 1919, there was no US state where it fell to it's pre-pandemic level, and the 1919 mortality rate was still double the pre-pandemic rate in some states such as California, South Carolina and Washington.

Australia Influenza Mortality jumped by 8% in 2019, from a year earlier.

Following variables were used for confounding adjustment. All variables are measured at the time of hospital admission.

In 2022, the highest death rate from influenza and pneumonia in Canada per 100,000 population was reported among those aged 90 years and older, with around *** deaths. Individuals between 85 and 89 years followed, with a mortality rate from influenza and pneumonia of almost *** deaths per 100,000 people. This statistic displays the death rate from influenza and pneumonia per 100,000 population in Canada during 2022, by age.

Highly pathogenic avian influenza virus (HPAIV) has caused extensive mortalities in wild birds, with a disproportionate impact on raptors since 2021. The population-level impact of HPAIV can be informed by telemetry studies that track large samples of initially healthy, wild birds. We leveraged movement data from 71 rough-legged hawks (Buteo lagopus) across all major North American migratory bird flyways concurrent with the 2022–2023 HPAIV outbreak and identified a total of 29 mortalities, of which 11 were confirmed, and an additional ~9 were estimated to have been caused by HPAIV. We estimated a 28% HPAIV cause-specific mortality rate among rough-legged hawks during a single year concurrent with the HPAIV outbreak in North America. Additionally, the overall annual mortality rate during the HPAIV outbreak (47%) was significantly higher than baseline annual mortality rates (3–17%), suggesting that HPAIV-caused deaths were additive above baseline mortality levels. HPAIV mortalities were concentrated within the Central and Atlantic flyways during pre-breeding migration and peaked in April 2022 when large-scale HPAIV mortalities were reported in other wild birds throughout North America. HPAIV exposure was most likely caused by scavenging or preying on infected waterfowl, as rough-legged hawks are known to opportunistically scavenge during the nonbreeding season. We utilized movement data to identify a continental-scale HPAIV cause-specific mortality event in rough-legged hawks that has the potential to exacerbate ongoing population declines. Our study highlights the usefulness of monitoring movement data to pinpoint sources of mortality that can help better understand the drivers of population change, even if studies are focused on other research questions.

In 2023, the number of deaths from influenza in Japan decreased to 1383 cases, which marked an increase compared to just ** cases in the previous year. The death rate from influenza amounted to *** death cases per 100,000 inhabitants in 2023.

BackgroundThe disease burden associated with influenza in developing tropical and subtropical countries is poorly understood owing to the lack of a comprehensive disease surveillance system and information-exchange mechanisms. The impact of influenza on outpatient visits, hospital admissions, and deaths has not been fully demonstrated to date in south China.MethodsA time series Poisson generalized additive model was used to quantitatively assess influenza-like illness (ILI) and influenza disease burden by using influenza surveillance data in Zhuhai City from 2007 to 2009, combined with the outpatient, inpatient, and respiratory disease mortality data of the same period.ResultsThe influenza activity in Zhuhai City demonstrated a typical subtropical seasonal pattern; however, each influenza virus subtype showed a specific transmission variation. The weekly ILI case number and virus isolation rate had a very close positive correlation (r = 0.774, P < 0.0001). The impact of ILI and influenza on weekly outpatient visits was statistically significant (P < 0.05). We determined that 10.7% of outpatient visits were associated with ILI and 1.88% were associated with influenza. ILI also had a significant influence on the hospitalization rates (P < 0.05), but mainly in populations 0.05). The impact of ILI on chronic obstructive pulmonary disease (COPD) was most significant (P < 0.05), with 33.1% of COPD-related deaths being attributable to ILI. The impact of influenza on the mortality rate requires further evaluation.ConclusionsILI is a feasible indicator of influenza activity. Both ILI and influenza have a large impact on outpatient visits. Although ILI affects the number of hospital admissions and deaths, we found no consistent influence of influenza, which requires further assessment.

Influenza surveillance is critical to monitoring the situation during epidemic seasons and predictive mathematic models may aid the early detection of epidemic patterns. The objective of this study was to design a real-time spatial predictive model of ILI (Influenza Like Illness) incidence rate in Catalonia using one- and two-week forecasts. The available data sources used to select explanatory variables to include in the model were the statutory reporting disease system and the sentinel surveillance system in Catalonia for influenza incidence rates, the official climate service in Catalonia for meteorological data, laboratory data and Google Flu Trend. Time series for every explanatory variable with data from the last 4 seasons (from 2010–2011 to 2013–2014) was created. A pilot test was conducted during the 2014–2015 season to select the explanatory variables to be included in the model and the type of model to be applied. During the 2015–2016 season a real-time model was applied weekly, obtaining the intensity level and predicted incidence rates with 95% confidence levels one and two weeks away for each health region. At the end of the season, the confidence interval success rate (CISR) and intensity level success rate (ILSR) were analysed. For the 2015–2016 season a CISR of 85.3% at one week and 87.1% at two weeks and an ILSR of 82.9% and 82% were observed, respectively. The model described is a useful tool although it is hard to evaluate due to uncertainty. The accuracy of prediction at one and two weeks was above 80% globally, but was lower during the peak epidemic period. In order to improve the predictive power, new explanatory variables should be included.

ObjectivesThe aim of this study is to estimate the excess mortality burden of influenza virus infection in China from 2012 to 2021, with a concurrent analysis of its associated disease manifestations.MethodsLaboratory surveillance data on influenza, relevant population demographics, and mortality records, including cause of death data in China, spanning the years 2012 to 2021, were incorporated into a comprehensive analysis. A negative binomial regression model was utilized to calculate the excess mortality rate associated with influenza, taking into consideration factors such as year, subtype, and cause of death.ResultsThere was no evidence to indicate a correlation between malignant neoplasms and any subtype of influenza, despite the examination of the effect of influenza on the mortality burden of eight diseases. A total of 327,520 samples testing positive for influenza virus were isolated between 2012 and 2021, with a significant decrease in the positivity rate observed during the periods of 2012–2013 and 2019–2020. China experienced an average annual influenza-associated excess deaths of 201721.78 and an average annual excess mortality rate of 14.53 per 100,000 people during the research period. Among the causes of mortality that were examined, respiratory and circulatory diseases (R&C) accounted for the most significant proportion (58.50%). Fatalities attributed to respiratory and circulatory diseases exhibited discernible temporal patterns, whereas deaths attributable to other causes were dispersed over the course of the year.ConclusionTheoretically, the contribution of these disease types to excess influenza-related fatalities can serve as a foundation for early warning and targeted influenza surveillance. Additionally, it is possible to assess the costs of prevention and control measures and the public health repercussions of epidemics with greater precision.

Influenza and pneumonia caused around 10.9 deaths in the U.S. per 100,000 population in 2023. Influenza, or the flu, is a viral infection that is highly contagious and especially common in the winter season. Influenza is a common cause of pneumonia, although most cases of the flu do not develop into pneumonia. Pneumonia is an infection or inflammation of the lungs and is particularly deadly among young children and the elderly. Influenza cases Influenza is very common in the United States, with an estimated 40 million cases reported in 2023-2024. Common symptoms of the flu include cough, fever, runny or stuffy nose, sore throat and headache. Symptoms can be mild but can also be severe enough to require medical attention. In 2023-2024, there were around 18 million influenza-related medical visits in the United States. Prevention To prevent contracting the flu, people can take everyday precautions such as regularly washing their hands and avoiding those who are sick, but the best way to prevent the flu is by receiving the flu vaccination every year. Receiving a flu vaccination is especially important for young children and the elderly, as they are most susceptible to flu complications and associated death. In 2024, around 70 percent of those aged 65 years and older received a flu vaccine, while only 33 percent of those aged 18 to 49 years had done so.

Body weight and survival rate of immunized mice upon lethal challenge with influenza virus.

Intensity level success rate (percentage) for prediction rates one (T+1) and two (T+2) weeks previously for each intensity level.