In 2023, there were approximately *** cases of breast cancer diagnosed per 100,000 women in Sweden. During 2021 the rate reached the highest annual rate of *** cases in the provided time interval, although there may have been some delay from 2020 when the COVID-19 pandemic stopped check-ups and screenings.

The number of new lung cancer cases diagnosed in Sweden fluctuated during the period from 2010 to 2023, and the highest number was in 2018 at ***** cases. Since then, cases have decreased, and there were ***** cases of lung cancer diagnosed in 2023.

All individuals diagnosed with cancer from 2000 to 2007 were identified in the Cancer Register of Southern Sweden, but only individuals who were also identified in the Population Register of Scania were included in this cohort. Age- and gender-matched controls were identified in the Population Register of Scania. The controls were reconciled with the cancer registry in southern Sweden so that they had no prior diagnosis of cancer and with the Population Register of Scania that they were alive at time of diagnosis to the matched case. Also spouses to cancer patients were used as controls.

For each individual, healthcare costs were monitored related to the date of diagnosis. Costs for outpatient care, inpatient care, number of days in hospital and medications were included. Costs were also calculated for the controls.

Other information available about the individuals in the cohort are age, sex, domicile, type of tumor and medication.

Purpose:

To study the health cost per individual in relation to mortality and comorbidity.

To investigate the global incidence of prostate cancer with special attention to the changing age structures. Data regarding the cancer incidence and population statistics were retrieved from the International Agency for Research on Cancer in World Health Organization. Eight developing and developed jurisdictions in Asia and the Western countries were selected for global comparison. Time series were constructed based on the cancer incidence rates from 1988 to 2007. The incidence rate of the population aged ≥ 65 was adjusted by the increasing proportion of elderly population, and was defined as the “aging-adjusted incidence rate”. Cancer incidence and population were then projected to 2030. The aging-adjusted incidence rates of prostate cancer in Asia (Hong Kong, Japan and China) and the developing Western countries (Costa Rica and Croatia) had increased progressively with time. In the developed Western countries (the United States, the United Kingdom and Sweden), we observed initial increases in the aging-adjusted incidence rates of prostate cancer, which then gradually plateaued and even decreased with time. Projections showed that the aging-adjusted incidence rates of prostate cancer in Asia and the developing Western countries were expected to increase in much larger extents than the developed Western countries.

Estimated parameters from calibration procedure.

Relative 1- and 5-year survival for lung cancer in Finland and Sweden.

Pancreatic cancer is predicted to become the second most common cause of cancer-related death by 2030. The objective of this study was to estimate the economic burden of pancreatic cancer for the years 2018 and 2030 based on changing demographics and incidence rates in Sweden. The incidence of pancreatic cancer in Sweden and additional relevant data were obtained from official statistics. A linear regression model and the mean incidence rates 2008–2018 were applied to calculate the incidence in 2030. An economic model based on the human capital method was created to calculate the indirect cost of pancreatic cancer in 2018 and 2030. Costs associated with surgery, radiology, oncology, and palliative care constituted the direct costs. A sensitivity analysis was performed. The incidence of pancreatic cancer in Sweden in the year 2018 was 1352 patients and projected to between 1554 (+15%) and 1736 (+28%) in 2030. The total cost was calculated to €125 million in 2018 and between €210 million (+68%) and €225 million (+80%) in 2030. The indirect cost in the ≤65-year-old group was €328,344 in 2018 and between €380,738 and €382,109 per individual in 2030. The economic burden of pancreatic cancer is expected to increase in Sweden by 2030 due to the increasing incidence of the disease and changing demographics. Pancreatic cancer is a growing health care problem in urgent need of advancements in prevention, early detection, treatment, and control of the disease.

In 2022, the incidence of lung cancer among men in Europe was highest in Hungary at ***** per 100,000, while Sweden had the lowest incidence. The incidence of lung cancer recorded among women in Denmark was over ** per 100,000 population. Across the European Union overall, the rate of lung cancer diagnoses was **** per 100,000 among men and **** per 100,000 among women. Smoking and lung cancer risk The connection between smoking and the increased risk of health problems is well established. As of 2021, Hungary had one of the highest daily smoking rates in Europe, with over a quarter of adults smoking daily in the Central European country. The only other countries with a higher share of smoking adults were Bulgaria and Turkey. A positive development though, is the share of adults smoking every day has decreased in almost every European country since 2011. The rise of vaping Originally marketed as a device to help smokers quit, e-cigarettes or vapes have seen increased popularity among people who never smoked cigarettes, especially young people. The use of vapes among young people was reported to be highest in Estonia, Czechia, and Ireland. The dangers of vaping have not been examined over the long term. In the EU there have been attempts to make ‘vapes’ less accessible and appealing for young people, which would include such things as banning flavors and stopping the sale of disposable e-cigarettes.

Number of invited women 23–60 years in Sweden 2013–2015, and attendance rates within 3 months and 1 year.

As of 2017, the **** year survival rate after being diagnosed with lung cancer in Sweden was ** percent. The five-year survival rate is the share of people who are alive five years after their diagnosis. In the provided time interval, lung cancer survival rates has increased in Sweden.

AAPC = Average Annual Percentage Change.

The crude incidence rates (IRs, per 1000 person-years) and incidence rate ratios (IRRs) of transient global amnesia (TGA) after cancer diagnosis, according to sex, calendar period of follow-up, age at follow-up, and previous TGA, a cohort study in Sweden, 2001–2009.

Mortality rate ratios (MRRs) are adjusted for calendar period of follow-up and level of education. The reference group is Sweden-born individuals. MRR values significantly different from 1.0 are highlighted in bold.*Categories with at least five cases of cancer mortality.

In Sweden between 1971 and 1975, around ** percent of women and ** percent of men who were diagnosed with melanoma survived for at least five years. By 2016 to 2020, the five-year survival rates from melanoma in the country had increased to almost ** percent among women and over ** percent among men.

High-risk human papillomavirus (hrHPV) infection is established as the major cause of invasive cervical cancer (ICC). However, whether hrHPV status in the tumor is associated with subsequent prognosis of ICC is controversial. We aim to evaluate the association between tumor hrHPV status and ICC prognosis using national registers and comprehensive human papillomavirus (HPV) genotyping.

In this nationwide population-based cohort study, we identified all ICC diagnosed in Sweden during the years 2002–2011 (4,254 confirmed cases), requested all archival formalin-fixed paraffin-embedded blocks, and performed HPV genotyping. Twenty out of 25 pathology biobanks agreed to the study, yielding a total of 2,845 confirmed cases with valid HPV results. Cases were prospectively followed up from date of cancer diagnosis to 31 December 2015, migration from Sweden, or death, whichever occurred first. The main exposure was tumor hrHPV status classified as hrHPV-positive and hrHPV-negative. The primary outcome was all-cause mortality by 31 December 2015. Five-year relative survival ratios (RSRs) were calculated, and excess hazard ratios (EHRs) with 95% confidence intervals (CIs) were estimated using Poisson regression, adjusting for education, time since cancer diagnosis, and clinical factors including age at cancer diagnosis and International Federation of Gynecology and Obstetrics (FIGO) stage.

Of the 2,845 included cases, hrHPV was detected in 2,293 (80.6%), and we observed 1,131 (39.8%) deaths during an average of 6.2 years follow-up. The majority of ICC cases were diagnosed at age 30–59 years (57.5%) and classified as stage IB (40.7%). hrHPV positivity was significantly associated with screen-detected tumors, young age, high education level, and early stage at diagnosis (p < 0.001). The 5-year RSR compared to the general female population was 0.74 (95% CI 0.72–0.76) for hrHPV-positive cases and 0.54 (95% CI 0.50–0.59) for hrHPV-negative cases, yielding a crude EHR of 0.45 (95% CI 0.38–0.52) and an adjusted EHR of 0.61 (95% CI 0.52–0.71). Risk of all-cause mortality as measured by EHR was consistently and statistically significantly lower for cases with hrHPV-positive tumors for each age group above 29 years and each FIGO stage above IA. The difference in prognosis by hrHPV status was highly robust, regardless of the clinical, histological, and educational characteristics of the cases. The main limitation was that, except for education, we were not able to adjust for lifestyle factors or other unmeasured confounders.

In conclusion, women with hrHPV-positive cervical tumors had a substantially better prognosis than women with hrHPV-negative tumors. hrHPV appears to be a biomarker for better prognosis in cervical cancer independent of age, FIGO stage, and histological type, extending information from already established prognostic factors. The underlying biological mechanisms relating lack of detectable tumor hrHPV to considerably worse prognosis are not known and should be further investigated.

Purpose:

To compile a comprehensive survival and HPV genotyping data and provide a large-scale population-based evaluation of the association between tumor high risk HPV status and prognosis of invasive cervical cancer.

This is an aggregated dataset (popmort_agg_2000_2015.dta) including the average survival rates of the Swedish female population, by age, for years 2000-2015. The dataset is generated based on the age-, gender- and calender year- specific survival rates of the Swedish population during the same calendar period.

The dataset included 4 variables: • Sex: Gender (all female): 2=female. • _age: Age (in years) • _year: Calendar year • Prob: Survival probability in corresponding age and calendar year

*Total number of studied individuals excluding those who died due to each type of cancer.

In 2022, almost ** percent of women in Sweden received a cervical cancer screening, the highest annual share in the provided time interval. Since 2012, the rate of cervical cancer screening has increased by around ** percent.

The incidence rate ratios (IRRs) of transient global amnesia after cancer diagnosis according to time since cancer diagnosis and by different cancer types, a cohort study in Sweden, 2001–2009.

The incidence of lung cancer in Sweden was highest among individuals with elementary school as their highest level of education. The lung cancer rate in this demographic was **** cases per hundred thousand individuals among men, and **** per hundred thousand among women. The incidence rate of lung cancer decreased by the higher educational level.

The highest cancer incidence in Sweden, by educational level, during the period from 2015 to 2019 was among men with elementary high school as their highest education. The rate of new cancer cases in this age group was 800.9 per hundred thousand inhabitants. The corresponding figure among women in this group was 780 cases per hundred thousand inhabitants.