Heart conditions were the most common causes of death in Mexico in 2023. During that period, more than ******* people died in the North American country as a result from said conditions. Diabetes mellitus ranked second, with over ******* deaths registered that year. Obesity in MexicoObesity and being overweight can worsen many risk factors for developing heart conditions, prediabetes, type 2 diabetes, and gestational diabetes, which in the case of a COVID-19 infection can lead to a severe course of the disease. In 2020, Mexico was reported as having one of the largest overweight and/or obese population in Latin America, with ** percent of people in the country having a body mass index higher than 25. In 2022, obesity was announced as being one of the most common illnesses experienced in Mexico, with over ******* cases estimated. In a decade from now, it is predicted that about *** million children in Mexico will suffer from obesity. If estimations are correct, this North American country will belong to the world’s top 10 countries with the most obese children in 2030. Physical activity in MexicoIt is not only a matter of food intake. A 2023 survey found, for instance, that only **** percent of Mexican population practiced sports and physical activities in their free time, a figure that has decreased in comparison to 2013. Less than ** percent of the physically active Mexicans practice sports for fun. However, the vast majority were motivated by health reasons.

In 2022, an estimated ** million cases of acute respiratory infections were reported in Mexico, making them the most common category of illnesses in the country. Urinary tract infections were the second most frequent ailments that year, with *** million cases. Risk factorsSeveral factors can cause respiratory infections; however, they can be exacerbated by activities such as smoking in patients with pre-existing health conditions. Though the smoker population in Mexico has generally declined in the last decade, figures still stand as high as **** million in 2020, and were projected to reach nearly **** million by 2025.Also a heart problemSmoking can also have detrimental effects on heart health. The second leading cause of death in Mexico in 2021 was heart conditions, with *** thousand deaths recorded. Demand for lifesaving transplants has also risen as a result. In 2021, ** patients were placed on the heart transplant waiting list in the North American country, and ** transplants were performed.

Background: Cardiovascular diseases are the leading causes of mortality worldwide. One reason behind this lethality lies in the fact that often cardiovascular illnesses develop into systemic failure due to the multiple connections to organismal metabolism. This in turn is associated with co-morbidities and multimorbidity. The prevalence of coexisting diseases and the relationship between the molecular origins adds to the complexity of the management of cardiovascular diseases and thus requires a profound knowledge of the genetic interaction of diseases.Objective: In order to develop a deeper understanding of this phenomenon, we examined the patterns of comorbidity as well as their genetic interaction of the diseases (or the lack of evidence of it) in a large set of cases diagnosed with cardiovascular conditions at the national reference hospital for cardiovascular diseases in Mexico.Methods: We performed a cross-sectional study of the National Institute of Cardiology. Socioeconomic information, principal diagnosis that led to the hospitalization and other conditions identified by an ICD-10 code were obtained for 34,099 discharged cases. With this information a cardiovascular comorbidity networks were built both for the full database and for ten 10-years age brackets. The associated cardiovascular comorbidities modules were found. Data mining was performed in the comprehensive ClinVar database with the disease names (as extracted from ICD-10 codes) to establish (when possible) connections between the genetic associations of the genetic interaction of diseases. The rationale is that some comorbidities may have a stronger genetic origin, whereas for others, the environment and other factors may be stronger.Results: We found that comorbidity networks are highly centralized in prevalent diseases, such as cardiac arrhythmias, heart failure, chronic kidney disease, hypertension, and ischemic diseases. Said comorbidity networks are actually modular on their connectivity. Modules recapitulate physiopathological commonalities, e.g., ischemic diseases clustering together. This is also the case of chronic systemic diseases, of congenital malformations and others. The genetic and environmental commonalities behind some of the relations in these modules were also found by resorting to clinical genetics databases and functional pathway enrichment studies.Conclusions: This methodology, hence may allow the clinician to look up for non-evident comorbidities whose knowledge will lead to improve therapeutically designs. By continued and consistent analysis of these types of patterns, we envisaged that it may be possible to acquire, strong clinical and basic insights that may further our advance toward a better understanding of cardiovascular diseases as a whole. Hopefully these may in turn lead to further development of better, integrated therapeutic strategies.

Turks and Caicos Islands saw a murder rate of ***** per 100,000 inhabitants, making it the most dangerous country for this kind of crime worldwide as of 2024. Interestingly, El Salvador, which long had the highest global homicide rates, has dropped out of the top 29 after a high number of gang members have been incarcerated. Meanwhile, Colima in Mexico was the most dangerous city for murders. Violent conflicts worldwide Notably, these figures do not include deaths that resulted from war or a violent conflict. While there is a persistent number of conflicts worldwide, resulting casualties are not considered murders. Partially due to this reason, homicide rates in Latin America are higher than those in Afghanistan or Syria. A different definition of murder in these circumstances could change the rate significantly in some countries. Causes of death Also, noteworthy is that murders are usually not random events. In the United States, the circumstances of murders are most commonly arguments, followed by narcotics incidents and robberies. Additionally, murders are not a leading cause of death. Heart diseases, strokes and cancer pose a greater threat to life than violent crime.