The demand for organ transplants in the United States continues to outpace supply, with over 105,000 individuals awaiting life-saving procedures as of May 2025. Kidneys remain the most sought-after organ, accounting for nearly 87 percent of all transplant candidates. This significant need underscores the ongoing challenges in organ donation and allocation across the country. Trends in transplantation rates While the waiting list for organs remains long, there have been notable improvements in transplantation rates for certain organs. For instance, the rate of lung transplants per million inhabitants in the United States nearly doubled from 4.9 in 2008 to 9.1 in 2023. This increase reflects advancements in medical technology and improved organ procurement processes. Liver transplants Liver transplants are the second most common type after kidney transplants. In 2024, individuals aged 50-64 received the highest number of liver transplants, with 4,949 procedures performed for this age group. California led the nation in liver transplants performed in 2024, followed by Texas, highlighting regional variations in organ availability and medical capabilities.

In 2024, there were ****** organ transplants in the United States. This was the highest number ever, with the second-highest number of transplants reported in 2023. In the United States, the most commonly transplanted organs are the kidneys, liver, and heart. Who donates organs in the United States? In 2024, there were just over ****** organ donors in the United States. Men accounted for around ** percent of organ donors that year. Some organs, such as a kidney, can be donated while the donor is alive, but most donations occur after the donor has deceased. For this reason, it is no surprise that most organ donors in the United States are older adults. In 2024, the highest number of organ donors were in the age group 50–64 years. Although the number of organ donors in the U.S. has increased gradually over the past few decades, those requiring an organ transplantation still far outnumber donors, with thousands currently on waiting lists to receive an organ transplantation that may save their life. Waiting lists for transplants In the United States, there were ******* candidates waiting for an organ transplantation as of May 2025. Around ** percent of these candidates were waiting for a kidney transplantation, while *****percent needed a liver transplant. Older adults are more likely to need an organ transplant than younger people, with those aged 50 to 64 years accounting for the highest number of candidates on organ donation waiting lists.

Introduction

Organ Transplantation Statistics: Organ transplantation is a medical procedure that involves replacing a damaged or failing organ with a healthy organ from a deceased or living donor.

It is a lifesaving treatment option for individuals with end-stage organ failure or certain debilitating conditions.

Organ Transplantation Statistics By Organs Types

• Kidneys
• Liver
• Heart
• Lungs
• Pancreas
• Intestines

This statistic depicts rates of selected organ transplantations in the United States in 2008 and 2023, per million inhabitants. In 2008, the rate of lung transplants per million inhabitants in the United States was 4.9. By 2023, this rate increased to 9.1.

Introduction

Organ Transplantation Statistics: Organ donation plays a crucial role in saving lives, providing people suffering from severe organ failure the opportunity to lead healthier, more fulfilling lives. Every year, millions of people around the world are waiting for organ transplants. Yet the gap between the growing demand and the limited supply of donor organs continues to expand. With ongoing advancements in transplant medicine, the need for donor organs has never been more urgent.

This section explores the current state of organ donation, highlighting key statistics that reveal the availability of organs, donor rates, and transplant success globally. These figures emphasize the significance of raising awareness and educating the public about organ donation to prevent lives from being lost due to a shortage of suitable organs.

The NIDDK Liver Transplantation Database was established to prospectively investigate questions related to the experience of patients evaluated for and undergoing liver transplantation. The LTD contains data for 1563 patients referred and evaluated for orthotopic liver transplantation (OLT) at three large liver transplant centers in the United States; of these patients, 916 underwent transplantation and were followed for 1 to 5 years.

All patients referred for OLT were screened for eligibility to be entered in the database, which required informed consent, no prior liver transplant, and availability to be followed. For each participant, standardized data was collected on demographics, medical history, preoperative and post-transplant symptoms and quality of life, post-transplant complications, and mortality. Liver biopsies and serum samples were also obtained pre- and post-transplantation at intervals specified in the study protocol.

Following primary data collection, which occurred from April 1990 to June 1994, the Liver Transplantation Database Follow Up (LTD2) study was conducted to prospectively generate detailed survival data from a large multicenter cohort of liver transplant recipients. This study observed the long-term outcomes of transplantation to examine adverse effects, assess risk factors, and determine long-term mortality rates and causes of death post-transplant.

Follow-up data was obtained for 798 transplant patients from 1998 to 2003 at 3 clinical centers. Cause of death was captured in the early (≤ 1 year) and late (> 1 year and > 5 years) post-transplant periods. Patient-related risk factors were analyzed for overall deaths as well as for each major cause of death in the late post-transplant period. Adverse events, including complications of transplantation and recurrence or development of disease, were monitored.

The follow-up study identified common etiologies and risk factors that contributed to the morality of liver transplant patients at various stages post-transplantation. Results showed that hepatic etiologies were the most frequent cause of death in the late post-transplant setting. In addition to malignancy and cardiovascular disease, renal failure was found to be an important and escalating cause of death in the late post-transplant setting. Ancillary studies have also been performed on LTD data to evaluate pathology reliability and cost of liver transplantation, as well as examine various characteristics or biomarkers of collected serum.

In 2023, the Americas reported the highest number of kidney transplants in the world. That year there were around 43,090 kidney transplants in the Americas, compared to 27,229 transplants in Europe, and 21,108 in the Western Pacific. Organ donation can be given through both a deceased and living donor if blood and oxygen are flowing through the organs until the time of recovery to ensure viability. What are the most transplanted organs? The most frequently transplanted organs worldwide are kidneys, livers, and hearts. However, kidneys account for the majority of organ transplantations with 65 percent of transplantations in 2023 involving kidneys. That year, around 24 percent of transplants were for livers and just six percent were for hearts. The rate of kidney transplants worldwide has increased over the past few years, reaching 18.5 transplants per million population in 2023, compared to a rate of 11.1 per million population in 2012. In 2023, there were a total of 111,135 kidney transplants worldwide. Organ transplants in the United States In 2023, there were 46,629 organ transplants in the United States, the highest number ever recorded. At that time, the rate of kidney transplants from living donors in the U.S. was 18.5 per million population, a slight decrease from a rate of 19.6 per million population in the year 2008. However, rates of liver, heart, and lung transplantations all increased over this period. Nevertheless, almost 105,000 people in the U.S. are currently waiting for an organ transplantation, highlighting the need for organ donation. Around 90,465 of these candidates are waiting for a kidney transplantation.

Dataset from Singapore Department of Statistics. For more information, visit https://data.gov.sg/datasets/d_eedb72c4e4e7f41dae0daa113cf789c1/view

This Dataset contains state and organ wise data related to total number of organs transplanted in India. NB: Data for 2024 is tentative.

Spain had the highest rate of organ transplants in 2023, at 120.4 per million population. This rate had increased by eight procedures compared with 2022. Portugal followed in 2023 with the second-highest rate at 90.2 transplants per million. Rate of specific transplants Spain had a rate of 77.7 kidney transplants per million population in 2023, the highest rate in Europe. Additionally, Spain had approximately 26.6 liver transplants per million in 2023, making it the fourth-highest rate in Europe behind only the rate of transplants in Croatia, Italy, and Belgium. Waiting for a transplant Spain had over 9.8 thousand patients active on the transplant waiting list in 2021, with 6.9 thousand of those waiting for a kidney transplant. This was lower the 18.8 thousand patients waiting for a kidney transplant in France, the highest amount in Europe.

The UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool, developed using advanced artificial intelligence (AI), significantly enhances the prediction of outcomes for deceased-donor kidney transplants in the UK. This study analyzed data from the UK Transplant Registry (UKTR), including 29,713 transplant cases between 2008 and 2022, to assess the predictive performance of three machine learning models: XGBoost, Random Survival Forest, and Optimal Decision Tree. Among these, XGBoost demonstrated exceptional performance with the highest concordance index of 0.74 and an area under the curve (AUC) consistently above 0.73, indicating robust discriminative ability and calibration. In comparison to the traditional Kidney Donor Risk Index (KDRI), which achieved a lower concordance index of 0.57, the UK-DTOP model marked a significant improvement, underscoring its superior predictive accuracy. The advanced capabilities of the XGBoost model were further highlighted through calibration assessments using the Integrated Brier Score (IBS), showing a score of 0.14, indicative of precise survival probability predictions. Additionally, unsupervised learning via k-means clustering was employed to identify five distinct clusters based on donor and transplant characteristics, uncovering nuanced insights into graft survival outcomes. These clusters were further analyzed using Bayesian Cox regression, which confirmed significant survival outcome variations across the clusters, thereby validating the model’s effectiveness in enhancing risk stratification. The UK-DTOP tool offers a comprehensive decision-support system that significantly refines pre-transplant decision-making. The study’s findings advocate for the adoption of AI-enhanced tools in healthcare systems to optimize organ matching and transplant success, potentially guiding future developments in global transplant practices.

The only national patient waiting list and an online database system, called UNet, that links all of the professionals involved in the donation and transplantation system for the collection, storage, analysis, and publication of all OPTN data pertaining to the patient waiting list, organ matching, and transplants. The system contains data regarding every organ donation and transplant event occurring in the U.S. since October 1, 1987. UNet is a fail-safe, 24/7, secure Internet-based transplant information database created to enable the nation''''s organ transplant institutions to: * register patients for transplants * match donated organs to waiting patients * manage the time-sensitive, life-critical data of all patients, before and after their transplants Data reports are available by type: National Data, Regional Data, State Data, Center Data, Build Advanced Report, and Annual Report Data. UNet is being used right now by all of the nation''''s organ transplant programs, organ procurement organizations, and histocompatibility (tissue typing) laboratories working cooperatively to efficiently share a limited number of donated organs among thousands of patients.

The kidney is the most transplanted organ worldwide, followed by the liver and the heart. In 2023, there were a total of ******* organ transplants worldwide. Organ transplantation is frequently the best or only treatment for end stage organ failure, although transplantation can be challenging and complex. Kidney transplantation Kidney transplantation, or renal transplantation, is by far the most common type of organ transplantation worldwide. Although end stage renal disease can be treated through other means, such as dialysis, kidney transplantation is largely viewed as the best treatment option. Most kidney transplants are done in the Americas and in Europe, where there are a larger number of donors and better access to such procedures. Organ donors Organs can be donated either from a living donor or a deceased donor, depending on the type of organ. Organ donation frequency is different from country to country, as laws that permit or refuse donation vary. Spain, the United States, and Portugal have the highest rates of deceased organ donors worldwide; however, there are still high numbers of patients waiting for organ transplants. In the United States alone, there are almost *** thousand candidates waiting for organ donations, the majority of which require a kidney transplantation.

In 2023/24, over 3.7 thousand organ transplants took place in the United Kingdom. The number of organ donors had increased year-on-year between 2014/15 and 2018/19, although numbers dropped in the subsequent COVID pandemic affected years. Type of organs donated The majority of transplants in the UK were kidney transplants, with over 2.4 thousand transplants of this kind carried out. A further 854 were liver transplants, followed by 237 heart transplants. The rate of organ donations in the United Kingdom amounted to 65 per million population in 2022. Transplant waiting list in the UK There were 5,898 patients on the active transplant list in the United Kingdom waiting for a kidney transplant as of March 2024. The number of individuals waiting for a kidney transplant was drastically higher than the number of patients waiting for any other organ in the country. Those waiting for a liver transplant had the second-highest number of active patients at 639, followed by 297 waiting for a kidney and pancreas transplant.

ABSTRACT Objectives: to indentify the time trend of rates of organs and tissues effective donors, of reports and types of transplanted organs per million people of the Brazilian population. Methods: ecological study, of time series, about reports of organ donations and on transplants. The data were provided by the Registro Brasileiro de Transplantes and analyzed using polynomial regression. Results an increasing trend was found for potential donors and effective donors, with an average increase of 2.33 and 0.92 per year, respectively. The South Region had the highest rate of potential donors (83.8) and effective donors (34.1) and the North Region, the lowest rate (20.2 and 3.9). The family refusal was the main obstacle to accomplish the donation. Conclusions the results show an increasing trend of potential donors and effective donors throughout Brazil, with emphasis on the southern region of the country. Among the main reasons for non-donation, it is worth emphasizing family refusal and medical contraindication prescription.

Additional file 3. Provincial Red Cross data.

Work items_month, January, February, March, April, May, June, July, August, September, October, November, December, Total

Lung Transplant Market Outlook

The global lung transplant market size was valued at approximately $1.5 billion in 2023 and is projected to reach $2.7 billion by 2032, growing at a compound annual growth rate (CAGR) of 6.8% during the forecast period. The primary growth drivers for this market include advancements in surgical techniques, improvements in immunosuppressive drugs, and an increasing prevalence of chronic respiratory diseases.

A major growth factor for the lung transplant market is the rising incidence of chronic respiratory diseases, including Chronic Obstructive Pulmonary Disease (COPD), pulmonary fibrosis, and cystic fibrosis. As lifestyles become more sedentary and pollution levels rise, the burden of respiratory diseases is expected to increase, fueling the demand for lung transplants. Moreover, early diagnosis and increased awareness about lung transplantation as a viable treatment option are also contributing to market growth.

Technological advancements have significantly impacted the lung transplant market. Innovations in surgical techniques, such as minimally invasive procedures, have improved patient outcomes and reduced recovery times. Additionally, advancements in immunosuppressive drugs have led to better management of transplant rejection, thereby increasing the success rates of lung transplants. The development of improved diagnostic tools and organ preservation methods also plays a crucial role in the market's growth.

Another critical factor driving market growth is the increasing number of organ donors and the establishment of national and international organ donation programs. Governments and non-profit organizations are actively promoting organ donation through extensive awareness campaigns. The implementation of robust organ donation systems has significantly reduced waiting times for lung transplants, thereby fostering market expansion. Furthermore, international collaborations and the sharing of best practices have enhanced the overall efficiency of lung transplant procedures globally.

In the broader field of organ transplantation, Kidney Transplant Surgery Instrument plays a crucial role in ensuring successful outcomes. These specialized instruments are designed to facilitate precise surgical interventions, minimizing the risk of complications and enhancing the overall success rates of kidney transplants. The advancements in these instruments have paralleled the progress seen in lung transplant procedures, reflecting a shared emphasis on improving patient care and surgical precision. As the demand for organ transplants continues to rise, the development and refinement of such instruments remain pivotal in supporting the growing needs of transplant surgeries globally.

Regionally, North America holds a significant share of the lung transplant market, driven by high healthcare expenditure, advanced medical infrastructure, and a well-established organ donation system. Europe follows closely, with countries like Germany, the UK, and France being major contributors. The Asia Pacific region is expected to witness the highest growth rate, owing to increasing healthcare investments, rising awareness about organ donation, and a growing prevalence of chronic respiratory diseases. Emerging markets in Latin America and the Middle East & Africa also show potential for growth, albeit at a slower pace, due to improving healthcare infrastructure and increasing government initiatives.

Type Analysis

The lung transplant market is segmented by type into single lung transplant, double lung transplant, and heart-lung transplant. Single lung transplants are often performed for patients with conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease (COPD). These procedures are less complex and have a shorter surgery duration compared to double lung transplants. However, the choice of transplant type largely depends on the underlying condition of the patient and the availability of donor organs.

Double lung transplants are typically performed for patients suffering from cystic fibrosis or severe pulmonary hypertension, where both lungs are severely affected. This type of transplant has a more extensive and complex surgical process but offers better long-term outcomes for certain conditions. The demand for double lung transplants is expected to rise due to the increasing prevalence of these conditions and improvements in surgical techniques and

Financial overview and grant giving statistics of Transplant Recipients International Organization Inc

Financial overview and grant giving statistics of Transplant Support Organization