Between January and August 2020, there has been approximately 48.2 thousand deaths in England and Wales with COVID-19 as an underlying cause. As illustrated in the table, the number of deaths as a result of COVID-19 are much higher than from either pneumonia or influenza. There has been over three times the number of deaths from COVID-19 than pneumonia and influenza so far in 2020. The overall number of confirmed COVID-19 cases in the UK can be found here. For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Facts and Figures page.

This statistic shows the deaths with influenza as an underlying cause in England and Wales in 2023, by age and gender. In this year, influenza was the underlying cause of *** deaths for women aged 90 years and over. Respiratory disease burden in the UK As of 2023, tuberculosis cases had also been on the rise, with ***** new cases and relapses reported in 2023. The ***** age group was most affected by this respiratory disease, accounting for approximately ***** cases. Pneumonia, another serious respiratory condition, caused over ***** deaths among women aged 90 and older in the same year, with a further ***** men in the same age group having pneumonia as their underlying cause of death. Vaccination prevalence and accessibility In the years 2014-2015, **** percent of individuals aged 65 and over in the North West of England were immunized against influenza. This was the region with the highest share of elderly vaccinated against influenza, while this figure was the lowest in London, around **** percent. Community pharmacies have played a crucial role in providing seasonal influenza vaccination services – as of 2023/24, ** percent of community pharmacies in the South of England offered influenza vaccination advanced service, while in London, the figure reached ** percent.

Over 12 million people in the United States died from all causes between the beginning of January 2020 and August 21, 2023. Over 1.1 million of those deaths were with confirmed or presumed COVID-19.

Vaccine rollout in the United States Finding a safe and effective COVID-19 vaccine was an urgent health priority since the very start of the pandemic. In the United States, the first two vaccines were authorized and recommended for use in December 2020. One has been developed by Massachusetts-based biotech company Moderna, and the number of Moderna COVID-19 vaccines administered in the U.S. was over 250 million. Moderna has also said that its vaccine is effective against the coronavirus variants first identified in the UK and South Africa.

For the week ending August 1, 2025, weekly deaths in England and Wales were 902 below the number expected, compared with 983 below what was expected in the previous week. In late 2022 and through early 2023, excess deaths were elevated for a number of weeks, with the excess deaths figure for the week ending January 13, 2023, the highest since February 2021. In the middle of April 2020, at the height of the COVID-19 pandemic, there were almost 12,000 excess deaths a week recorded in England and Wales. It was not until two months later, in the week ending June 19, 2020, that the number of deaths began to be lower than the five-year average for the corresponding week. Most deaths since 1918 in 2020 In 2020, there were 689,629 deaths in the United Kingdom, making that year the deadliest since 1918, at the height of the Spanish influenza pandemic. As seen in the excess death figures, April 2020 was by far the worst month in terms of deaths during the pandemic. The weekly number of deaths for weeks 16 and 17 of that year were 22,351, and 21,997 respectively. Although the number of deaths fell to more usual levels for the rest of that year, a winter wave of the disease led to a high number of deaths in January 2021, with 18,676 deaths recorded in the fourth week of that year. For the whole of 2021, there were 667,479 deaths in the UK, 22,150 fewer than in 2020. Life expectancy in the UK goes into reverse In 2022, life expectancy at birth for women in the UK was 82.6 years, while for men it was 78.6 years. This was the lowest life expectancy in the country for ten years, and came after life expectancy improvements stalled throughout the 2010s, and then declined from 2020 onwards. There is also quite a significant regional difference in life expectancy in the UK. In the London borough of Kensington and Chelsea, for example, the life expectancy for men was 81.5 years, and 86.5 years for women. By contrast, in Blackpool, in North West England, male life expectancy was just 73.1 years, while for women, life expectancy was lowest in Glasgow, at 78 years.

There were 667,479 deaths in the United Kingdom in 2021, compared with 689,629 in 2020. Between 2003 and 2011, the annual number of deaths in the UK fell from 612,085 to just over 552,232. Since 2011 however, the annual number of annual deaths in the United Kingdom has steadily grown, with the number recorded in 2020, the highest since 1918 when there were 715,246 deaths. Both of these spikes in the number of deaths can be attributed to infectious disease pandemics. The great influenza pandemic of 1918, which was at its height towards the end of World War One, and the COVID-19 pandemic, which caused a large number of deaths in 2020.  Impact of the COVID-19 pandemic The weekly death figures for England and Wales highlight the tragic toll of the COVID-19 pandemic. In two weeks in April of 2020, there were 22,351 and 21,997 deaths respectively, almost 12,000 excess deaths in each of those weeks. Although hospitals were the most common location of these deaths, a significant number of these deaths also took place in care homes, with 7,911 deaths taking place in care homes for the week ending April 24, 2020, far higher than usual. By the summer of 2020, the number of deaths in England and Wales reached more usual levels, before a second wave of excess deaths hit the country in early 2021. Although subsequent waves of COVID-19 cases resulted in far fewer deaths, the number of excess deaths remained elevated throughout 2022. Long-term life expectancy trends As of 2022 the life expectancy for men in the United Kingdom was 78.57, and almost 82.57 for women, compared with life expectancies of 75 for men and 80 for women in 2002. In historical terms, this is a major improvement in relation to the mid 18th century, when the overall life expectancy was just under 39 years. Between 2011 and 2017, improvements in life expectancy in the UK did start to decline, and have gone into reverse since 2018/20. Between 2020 and 2022 for example, life expectancy for men in the UK has fallen by over 37 weeks, and by almost 23 weeks for women, when compared with the previous year.

Since 2020, outbreaks of high pathogenicity avian influenza (HPAI) have led to a global rise in deaths of both wild birds and poultry, as well as an increase in reported cases of HPAI detected in mammals. These outbreaks have had negative impacts on poultry producers, trade, and wild bird populations. Risk governance frameworks for emerging infectious diseases such as HPAI encourage outbreak policies to be grounded in a variety of stakeholder perspectives and for there to be effective, transparent communication between all those involved. However, the COVID-19 pandemic exemplified how collaboration is not always easy to implement, leading to potentially sub-optimal outbreak response processes. To our best knowledge, there is limited to no current research assessing the stakeholder landscape and outbreak decision-making and response processes in the United Kingdom (UK) and United States of America (USA) for the recent HPAI outbreak. In this study, 20 key stakeholders involved in outbreak decision-making and response in the United Kingdom and United States were asked to provide their insights into the structure of stakeholder landscape, communication pathways, and challenges in decision-making and response implementation for their respective countries. Semi-structured interviews were conducted with participants from the United Kingdom and United States; participants included policy advisors, veterinarians, researchers, and poultry industry representatives all involved in HPAI outbreak processes in their country. From these interviews, stakeholder maps for all those involved in HPAI decision-making and response were created for the UK and USA. This study concluded that smallholders and backyard poultry owners need to be better represented in policy-industry communication pathways and that improved information sharing at the policy-science and policy-industry interfaces is essential to ensure an efficient outbreak response.

Baseline characteristics and vaccine uptake.

At the beginning of the 1840s, life expectancy from birth in Ireland was just over 38 years. However, this figure would see a dramatic decline with the beginning of the Great Famine in 1845, and dropped below 21 years in the second half of the decade (in 1849 alone, life expectancy fell to just 14 years). The famine came as a result of a Europe-wide potato blight, which had a disproportionally devastating impact on the Irish population due to the dependency on potatoes (particularly in the south and east), and the prevalence of a single variety of potato on the island that allowed the blight to spread faster than in other areas of Europe. Additionally, authorities forcefully redirected much of the country's surplus grain to the British mainland, which exacerbated the situation. Within five years, mass starvation would contribute to the deaths of over one million people on the island, while a further one million would emigrate; this also created a legacy of emigration from Ireland, which saw the population continue to fall until the mid-1900s, and the total population of the island is still well below its pre-famine level of 8.5 million people.

Following the end of the Great Famine, life expectancy would begin to gradually increase in Ireland, as post-famine reforms would see improvements in the living standards of the country’s peasantry, most notably the Land Wars, a largely successful series of strikes, boycotts and protests aimed at reform of the country's agricultural land distribution, which began in the 1870s and lasted into the 20th century. As these reforms were implemented, life expectancy in Ireland would rise to more than fifty years by the turn of the century. While this rise would slow somewhat in the 1910s, due to the large number of Irish soldiers who fought in the First World War and the Spanish Flu pandemic, as well as the period of civil unrest leading up to the island's partition in 1921, life expectancy in Ireland would rise greatly in the 20th century. In the second half of the 20th century, Ireland's healthcare system and living standards developed similarly to the rest of Western Europe, and today, it is often ranks among the top countries globally in terms of human development, GDP and quality of healthcare. With these developments, the increase in life expectancy from birth in Ireland was relatively constant in the first century of independence, and in 2020 is estimated to be 82 years.

Life expectancy in India was 25.4 in the year 1800, and over the course of the next 220 years, it has increased to almost 70. Between 1800 and 1920, life expectancy in India remained in the mid to low twenties, with the largest declines coming in the 1870s and 1910s; this was because of the Great Famine of 1876-1878, and the Spanish Flu Pandemic of 1918-1919, both of which were responsible for the deaths of up to six and seventeen million Indians respectively; as well as the presence of other endemic diseases in the region, such as smallpox. From 1920 onwards, India's life expectancy has consistently increased, but it is still below the global average.