The United States chemical industry's total revenue (referred to as final sales by the source) amounted to *** billion U.S. dollars in 2023. That was a significant decrease compared to the U.S. chemical sector's revenue in 2015, which amounted to nearly *** billion U.S. dollars. The U.S. final sales figure is a calculation of the total value of chemical shipments plus imports, minus exports. The United States is home to several of the world's leading chemical companies.

Graph and download economic data for Real Gross Domestic Product: Chemical Manufacturing (325) in the United States (USCHEMMANRGSP) from 1997 to 2024 about chemicals, nondurable goods, GSP, private industries, production, goods, private, manufacturing, real, industry, GDP, and USA.

In 2022, the chemical production index in the United States was recorded at 95.5 indicating a decrease from its 2017 baseline value of 100. Several factors could have contributed to this decline. Economic fluctuations, market dynamics, and regulatory changes are among the key influencers shaping the chemical industry.

The production volume of the chemical industry in the United States increased by *** percent in 2022, but this chemical output is expected to fall by *** percent in 2023.

Market Size statistics on the Chemical Product Manufacturing industry in the US

Graph and download economic data for Producer Price Index by Industry: Chemical Manufacturing (PCU325325) from Dec 1984 to Aug 2025 about chemicals, manufacturing, PPI, industry, inflation, price index, indexes, price, and USA.

Comprehensive dataset containing 871 verified Chemical industry businesses in United States with complete contact information, ratings, reviews, and location data.

Graph and download economic data for Employment for Manufacturing: Basic Chemical Manufacturing (NAICS 3251) in the United States (IPUEN3251W200000000) from 1987 to 2024 about chemicals, NAICS, IP, manufacturing, employment, and USA.

Graph and download economic data for Real Sectoral Output for Manufacturing: Chemical Manufacturing (NAICS 325) in the United States (IPUEN325T011000000) from 1988 to 2024 about output, chemicals, NAICS, IP, manufacturing, and USA.

Graph and download economic data for All Employees, Chemical Manufacturing (CES3232500001) from Jan 1990 to Sep 2025 about chemicals, nondurable goods, establishment survey, goods, employment, and USA.

The industry’s revenue dynamics reflect diverse demand streams tied to downstream industries, including plastics, construction, automotive, agriculture and pharmaceuticals. Demand for specialty coatings and advanced composites tracks closely with expanding US infrastructure investments and automotive electrification initiatives, prompting manufacturers to recalibrate product development towards performance-enhancing additives and high-durability polymers. Regulatory scrutiny over hazardous emissions and the accelerated shift to digitalized process control have prompted significant investments in compliance technologies and automation, effectively raising the baseline for operational resilience and efficiency. Strategic alignment with end-user innovation cycles remains critical for revenue continuity as producers respond to shifting material performance specifications and safety standards. Over the past five years, the industry balanced cyclical headwinds, including swings in petrochemical feedstock pricing and trade policy uncertainty, with ongoing shifts toward customized product lines and higher-margin specialty formulations. Manufacturers widened portfolios, expanding into water treatment reagents and crop-protection additives as a reaction to changing environmental policy and shifting agri-business demand. Supply chain resilience was bolstered by nearshoring raw material inputs, allowing producers to mitigate the logistical shockwaves from tariff escalations and shipping disruptions. Domestic demand complemented export-led growth because of infrastructure renewal, reshaping capital expenditure priorities and supporting profit margin stabilization even as input cost pressures remained volatile. Industry revenue has been expanding at a CAGR of 1.1% over the past five years and is expected to total $46.7 billion in 2025, when revenue will jump by an estimated 6.8%. Looking forward, manufacturers will prioritize advanced process automation and resource-efficient formulation technologies, with IoT-enabled monitoring and digital twin solutions gaining traction to maximize production reliability and yield. Revisions to TSCA chemical reporting, escalating greenhouse gas emission limits and potential modifications to US-Mexico-Canada Agreement chemicals trade provisions will directly impact operational costs and cross-border competitiveness. Incumbents face mounting requirements for portfolio modernization, particularly transitioning legacy chemistries to bio-based alternatives, while market entrants may target specialty segments such as electronic coatings or low-GWP refrigerant blends. Strategic imperatives center on leveraging proprietary formulations and manufacturing agility to navigate regulatory complexity and capture premium-positioned growth opportunities in downstream innovation-driven submarkets. Industry revenue is expected to inch upward at a CAGR of 0.9% to $48.8 billion over the five years to 2030.

With over 60 billion U.S. dollars of chemical exports in 2022, Texas reported the highest export value among all U.S. states. Louisiana came in second that year with 13.17 billion U.S. dollars, with these top two states accounting for over half of the total chemical exports in the country. Other significant states in terms of export values included New Jersey, California, and Illinois. Overview of the U.S. chemical industry The chemical industry in the United States is a significant sector that generates billions of dollars in revenue annually. In 2021, chemical shipments from the United States were worth 769 billion U.S. dollars while the industry's total revenue was valued at 492.4 billion U.S. dollars that year. Although this figure represents a reduction compared to its maximum total revenue of 818.2 billion U.S. dollars, recorded in 2015, the United States is still home to several of the world's leading chemical companies. As such, the value of the United States' chemical exports has increased from around 76.8 billion U.S. dollars in 2001 to approximately 233 billion U.S. dollars in 2021.

The global chemical industry and its key players The global chemical industry is a lucrative sector that generates billions of dollars in revenue annually. In 2021, the chemical industry's total worldwide revenue stood at 4.73 trillion U.S. dollars. China leads the world in chemical exports, with exports amounting to over 106 billion U.S. dollars in 2021, followed by the United States with exports worth over 56 billion U.S. dollars that year. China is also the largest consumer of chemicals, with a consumption value of 1.76 trillion euros in 2021. In comparison, the United States' chemical consumption amounted to around 412 billion euros in the same year.

The United States Water Treatment Chemicals Market Report is Segmented by Product Type (Biocides and Disinfectants, Coagulants and Flocculants, Corrosion and Scale Inhibitors, and More), End-User Industry (Power, Oil and Gas, Chemical Manufacturing, Mining and Mineral Processing, Municipal, Food and Beverage, and More), and Geography (Northeast, Midwest, South, and West). The Market Forecasts are Provided in Terms of Value (USD).

Graph and download economic data for Capital Costs for Manufacturing: Other Chemical Product and Preparation Manufacturing (NAICS 3259) in the United States (IPUEN3259C020000000) from 1987 to 2022 about cost, chemicals, NAICS, capital, IP, production, manufacturing, and USA.

View quarterly updates and historical trends for US Capacity Utilization: Chemical Manufacturing. from United States. Source: Federal Reserve. Track econo…

The United States Chemical Warehousing and Storage Market Report is Segmented by Warehouse Type (General Warehousing, Specialty Chemical Warehouse, and More), by Chemical Type (Flammable Liquids, Corrosives, and More), by End-User Industry (Basic Chemicals Manufacturing, Specialty Chemicals Manufacturing, and More), and by Geography (Northeast, and More). The Market Forecasts are Provided in Terms of Value (USD).

This paper argues that the concepts of “normal” reproductive development that biologists rely upon are undergirded by heterosexism, ableism, and white supremacism, even if implicitly. We illustrate our argument by critically analyzing toxicology’s use of reproductive fitness, focusing on the field of endocrine- disrupting chemicals (EDCs). Toxicology both informs and is informed by fundamental evolutionary and ecological questions, as well as environmental health. Throughout, biologists overwhelmingly assume that “abnormal” reproductive physiologies are both generated by EDC exposure and necessarily threaten species survival. Such assumptions unwittingly obscure fundamental scientific insights while further discriminating against queer, trans, nonbinary, and differently-abled human communities. We agree that scientists should be sounding the alarm over unavoidable, unevenly distributed, and highly hazardous EDC exposures—which cause metabolic dysregulation, cancer, and death—but not because gonads and genitals look different. Instead, we encourage scientists to confront directly how chemical corporations profit from innumerable, irreversible harms to ecological and societal wellbeing, harms which may very well have nothing to do with gonads or genitals. We close with three specific suggestions to help scientists dismantle the human hierarchies embedded into biological frameworks, toward better science and environmental justice. By refusing the oppressive social ideologies assumed by prior research, toxicological and biological scientists will offer exciting new insights into evolutionary processes and urgent, justice-centered findings for environmental health.

Methods The raw data were downloaded from:

American Chemistry Council. 2020. “Chemical Activity Barometer.” American Chemistry Council. (https://www.americanchemistry.com/chemistry-in-america/data-industry-statistics/chemical-activity-barometer).

Board of Governors of the Federal Reserve System. 2021. “Data: Industrial Production and Capacity Utilization - G.17.” Industrial Production and Capacity Utilization - G.17. (https://www.federalreserve.gov/releases/g17/download.htm).

First author Melina Packer aggregated the data (average annual industrial chemical production, in metric tons, 1919-2019) to create the figure in the paper.

Graph and download economic data for Manufacturers' Value of Shipments: Chemical Products (U25SVS) from Jan 1992 to Aug 2025 about shipments, chemicals, nondurable goods, production, goods, manufacturing, industry, and USA.

The United States Construction Chemicals Report is Segmented by Product (Adhesives, Anchors and Grouts, Concrete Admixtures, Concrete Protective Coatings, Flooring Resins, Repair and Rehabilitation Chemicals, Sealants, Surface-Treatment Chemicals, and More), and End-Use Sector (Commercial, Industrial and Institutional, Infrastructure, and Residential). The Market Forecasts are Provided in Terms of Value (USD).

Graph and download economic data for Labor Productivity for Manufacturing: Chemical Manufacturing (NAICS 325) in the United States (IPUEN325L000000000) from 1987 to 2024 about productivity, chemicals, NAICS, IP, labor, manufacturing, and USA.