As of March 10, 2023, there have been 1.1 million deaths related to COVID-19 in the United States. There have been 101,159 deaths in the state of California, more than any other state in the country – California is also the state with the highest number of COVID-19 cases.

The vaccine rollout in the U.S. Since the start of the pandemic, the world has eagerly awaited the arrival of a safe and effective COVID-19 vaccine. In the United States, the immunization campaign started in mid-December 2020 following the approval of a vaccine jointly developed by Pfizer and BioNTech. As of March 22, 2023, the number of COVID-19 vaccine doses administered in the U.S. had reached roughly 673 million. The states with the highest number of vaccines administered are California, Texas, and New York.

Vaccines achieved due to work of research groups Chinese authorities initially shared the genetic sequence to the novel coronavirus in January 2020, allowing research groups to start studying how it invades human cells. The surface of the virus is covered with spike proteins, which enable it to bind to human cells. Once attached, the virus can enter the cells and start to make people ill. These spikes were of particular interest to vaccine manufacturers because they hold the key to preventing viral entry.

As of June 6, 2022, the novel coronavirus SARS-CoV-2 that originated in Wuhan, the capital of Hubei province in China, had infected over 2.1 million people and killed 14,612 in the country. Hong Kong is currently the region with the highest active cases in China.

From Wuhan to the rest of China

In late December 2019, health authorities in Wuhan detected several pneumonia cases of unknown cause. Most of these patients had links to the Huanan Seafood Market. With Chinese New Year approaching, millions of Chinese migrant workers travelled back to their hometowns for the celebration. Before the start of the travel ban on January 23, around five million people had left Wuhan. By the end of January, the number of infections had surged to over ten thousand. The death toll from the virus exceeded that of the SARS outbreak a few days later. On February 12, thousands more cases were confirmed in Wuhan after an improvement to the diagnosis method, resulting in another sudden surge of confirmed cases. On March 31, 2020, the National Health Commission (NHC) in China announced that it would begin reporting the infection number of symptom-free individuals who tested positive for coronavirus. On April 17, 2020, health authorities in Wuhan revised its death toll, adding 50 percent more fatalities. After quarantine measures were implemented, the country reported no new local coronavirus COVID-19 transmissions for the first time on March 18, 2020.

The overloaded healthcare system

In Wuhan, 28 hospitals were designated to treat coronavirus patients, but the outbreak continued to test China’s disease control system and most of the hospitals were soon fully occupied. To combat the virus, the government announced plans to build a new hospital swiftly. On February 3, 2020, Huoshenshan Hospital was opened to provide an additional 1,300 beds. Due to an extreme shortage of health-care professionals in Wuhan, thousands of medical staff from all over China came voluntarily to the epicenter to offer their support. After no new deaths reported for first time, China lifted ten-week lockdown on Wuhan on April 8, 2020. Daily life was returning slowly back to normal in the country.

The graph illustrates the number of deaths per day in the United States from 1950 to 2025. The x-axis represents the years, abbreviated from '50 to '24, while the y-axis indicates the daily number of deaths. Over this 75-year period, the number of deaths per day ranges from a low of 4,054 in 1950 to a high of 9,570 in 2021. Notable figures include 6,855 deaths in 2010 and 8,333 in 2024. The data shows a general upward trend in daily deaths over the decades, with recent years experiencing some fluctuations. This information is presented in a line graph format, effectively highlighting the long-term trends and yearly variations in daily deaths across the United States.