In 2019, private label analgesic-internal tablet brands were responsible for 34.3 percent of total dollar sales in the United States. The Advil brand generated 13.1 percent of total dollar sales that same period.

Advil was the leading name-brand internal analgesic tablet in the United States in 2019, not including private label. In that year, Advil generated 449.5 million U.S. dollars in sales, while private label internal analgesic tablet sales amounted to nearly 1.18 billion U.S. dollars. Internal analgesics are often used to treat minor aches and pains, such as headaches.

Over-The-Counter products In 2017, total OTC drug retail sales amounted to 34.3 billion U.S. dollars, up from 34 billion dollars the previous year. The largest segment of the OTC medicines market in the United States is vitamins and minerals, followed by cold, cough, and flu medicines.

Drugstore and pharmacy retail in the U.S. U.S. pharmacy and drug stores generated sales of 276.92 billion U.S. dollars in 2017. CVS Health and Walgreens were the two leading drug store chains in the United States based on prescription sales, at 60.8 billion U.S. dollars and 56.5 billion U.S. dollars respectively. In 2017, CVS Health operated 9,778 locations, more than any other drug store chain in the United States.