From 2018 to 2023, heart disease and cancer accounted for the highest share of deaths in the United States. In 2020 and 2021, COVID-19 became the third leading cause of death, accounting for around 12 percent of all deaths in 2021. However, by 2023, COVID-19 was responsible for only 1.6 percent of deaths, making it the tenth leading cause of death. This statistic shows the distribution of the 10 leading causes of death in the United States from 2018 to 2023.

During the months December 2020, January 2021, and February 2021, COVID-19 was the leading cause of death in the United States based on the average number of daily deaths. Heart disease and cancer are usually the number one and number two leading causes of death, respectively. This statistic shows the average number of daily deaths in the United States among the leading causes of death from March 2020 to September 2022.