Voltage imaging enables monitoring neural activity at sub-millisecond and sub-cellular scale, unlocking the study of subthreshold activity, synchrony, and network dynamics with unprecedented spatio-temporal resolution. However, high data rates (>800MB/s) and low signal-to-noise ratios create bottlenecks for analyzing such datasets. Here we present VolPy, an automated and scalable pipeline to pre-process voltage imaging datasets.VolPy features motion correction, memory mapping, automated segmentation,denoising and spike extraction, all built on a highly parallelizable, modular, and extensible framework optimized for memory and speed. To aid automated segmentation,we introduce a corpus of 24 manually annotated datasets from different preparations,brain areas and voltage indicators. We benchmark VolPy against ground truth segmentation, simulations and electrophysiology recordings, and we compare its performance with existing algorithms in detecting spikes. Our results indicate that VolPy’s performance in spike extraction and scalability are state-of-the-art.

File names contain 'L1'(mouse cortex) or 'TEG'(zebrafish tegmental area) are from the following paper:

Abdelfattah AS, Kawashima T, Singh A, Novak O, Liu H, Shuai Y, et al. Bright and photostable chemigenetic indicators for extended in vivo voltage imaging.Science. 2019;365(6454):699–704. doi:10.1126/science.aav6416.

File names contain 'HPC'(mouse hippocampus) are from the following paper:

Adam Y, Kim JJ, Lou S, Zhao Y, Xie ME, Brinks D, et al. Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics.Nature. 2019;569(7756):413.

For each type of datasets, number of datasets, number of neurons, recall, precision, F1 score for training and validation computed by stratified cross-validation are provided.

For each type of dataset the name, organism, brain region, source, imaging rate, voltage indicator, and total number of neurons selected by the manual annotators in GT (consensus, (labeler 1, labeler 2, labeler 3)) are given.

An excel file contains data for generating Figs 3B, 3C, 3D, 4C, 4D, 4E, 5B, 5D, 6A, 6B, 6C and 6D. (XLSX)

Measurements made off the San Diego, Californian coast in 1999.

This dataset provides information about the number of properties, residents, and average property values for Volpi Drive cross streets in Stockton, CA.

This dataset provides information about the number of properties, residents, and average property values for Volpe Road cross streets in Plymouth Meeting, PA.

This dataset contains data on original and post-calibration mileposts, Traffic Message Channel location codes (TMC), Truck Travel Time Reliability Index, Travel Time Index (TTI), TMC mileage, and corridor identification segment for the destination to origin direction of the National Performance Monitoring Research Data Set (NPMRDS) network.

Financial overview and grant giving statistics of Volpe Memorial Fund

A Civil Service List consists of all candidates who passed an exam, ranked in score order. An established list is considered active for no less than one year and no more than four years from the date of establishment. For more information visit DCAS’ “Work for the City” webpage at: http://www.nyc.gov/html/dcas/html/work/work.shtml

Volpe. (2004). Hypertension Surveys. High Blood Pressure & Cardiovascular Prevention. DOI: 10.2165/00151642-200411040-00001

This dataset contains data on bridge conditions and clearance for the study corridors in the Importance of Highways to U.S. Agriculture Report. The Volpe Center derived this study specific dataset from the Federal Highway Administration's (FHWA’s) National Bridge Inventory (NBI) data.

Michelle Volpe-Kohler is the senior manager of marketing and communications in the People Resources Department at the Federal Reserve Bank of Cleveland.

Volpe. (2005). Head-to-Head Intervention Trials in Hypertension. High Blood Pressure & Cardiovascular Prevention. DOI: 10.2165/00151642-200512010-00001

This dataset provides information about the number of properties, residents, and average property values for Volpe Way cross streets in Smyrna, DE.

Volpi Concerie Spa Export Import Data. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.

Comprehensive YouTube channel statistics for Volpe Where Are You, featuring 982,000 subscribers and 145,817,442 total views. This dataset includes detailed performance metrics such as subscriber growth, video views, engagement rates, and estimated revenue. The channel operates in the Lifestyle category and is based in US. Track 385 videos with daily and monthly performance data, including view counts, subscriber changes, and earnings estimates. Analyze growth trends, engagement patterns, and compare performance against similar channels in the same category.

Track the VOLPE in real-time with AIS data. TRADLINX provides live vessel position, speed, and course updates. Search by MMSI: 319296600, IMO: 1072232

Apportionment file 11477596 retrieved from OMB public records

Volpe Import Inc Export Import Data. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.