14 datasets found
  1. Rates and Trends in Heart Disease and Stroke Mortality Among US Adults (35+)...

    • catalog.data.gov
    • healthdata.gov
    • +4more
    Updated Jun 28, 2025
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    Centers for Disease Control and Prevention (2025). Rates and Trends in Heart Disease and Stroke Mortality Among US Adults (35+) by County, Age Group, Race/Ethnicity, and Sex – 2000-2019 [Dataset]. https://catalog.data.gov/dataset/rates-and-trends-in-heart-disease-and-stroke-mortality-among-us-adults-35-by-county-a-2000-45659
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    Dataset updated
    Jun 28, 2025
    Dataset provided by
    Centers for Disease Control and Preventionhttp://www.cdc.gov/
    Description

    This dataset documents rates and trends in heart disease and stroke mortality. Specifically, this report presents county (or county equivalent) estimates of heart disease and stroke death rates in 2000-2019 and trends during two intervals (2000-2010, 2010-2019) by age group (ages 35–64 years, ages 65 years and older), race/ethnicity (non-Hispanic American Indian/Alaska Native, non-Hispanic Asian/Pacific Islander, non-Hispanic Black, Hispanic, non-Hispanic White), and sex (women, men). The rates and trends were estimated using a Bayesian spatiotemporal model and a smoothed over space, time, and demographic group. Rates are age-standardized in 10-year age groups using the 2010 US population. Data source: National Vital Statistics System.

  2. Cardiovascular Disease Death Rates, Trends, and Excess Death Rates Among US...

    • catalog.data.gov
    • healthdata.gov
    • +2more
    Updated Feb 3, 2025
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    Centers for Disease Control and Prevention (2025). Cardiovascular Disease Death Rates, Trends, and Excess Death Rates Among US Adults (35+) by County and Age Group – 2010-2020 [Dataset]. https://catalog.data.gov/dataset/cardiovascular-disease-death-rates-trends-and-excess-death-rates-among-us-adults-35-b-2010
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    Dataset updated
    Feb 3, 2025
    Dataset provided by
    Centers for Disease Control and Preventionhttp://www.cdc.gov/
    Description

    This dataset documents cardiovascular disease (CVD) death rates, relative and absolute excess death rates, and trends. Specifically, this report presents county (or county equivalent) estimates of CVD death rates in 2000-2020, trends during 2010-2019, and relative and absolute excess death rates in 2020 by age group (ages 35–64 years, ages 65 years and older). All estimates were generated using a Bayesian spatiotemporal model and a smoothed over space, time, and 10-year age groups. Rates are age-standardized in 10-year age groups using the 2010 US population. Data source: National Vital Statistics System.

  3. Rates and Trends in Hypertension-related Cardiovascular Disease Mortality...

    • data.virginia.gov
    • healthdata.gov
    • +5more
    csv, json, rdf, xsl
    Updated Aug 24, 2023
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    Centers for Disease Control and Prevention (2023). Rates and Trends in Hypertension-related Cardiovascular Disease Mortality Among US Adults (35+) by County, Age Group, Race/Ethnicity, and Sex – 2000-2019 [Dataset]. https://data.virginia.gov/dataset/rates-and-trends-in-hypertension-related-cardiovascular-disease-mortality-among-us-ad-2000-2019
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    csv, xsl, rdf, jsonAvailable download formats
    Dataset updated
    Aug 24, 2023
    Dataset provided by
    Centers for Disease Control and Preventionhttp://www.cdc.gov/
    Description

    This dataset documents rates and trends in local hypertension-related cardiovascular disease (CVD) death rates. Specifically, this report presents county (or county equivalent) estimates of hypertension-related CVD death rates in 2000-2019 and trends during two intervals (2000-2010, 2010-2019) by age group (ages 35–64 years, ages 65 years and older), race/ethnicity (non-Hispanic American Indian/Alaska Native, non-Hispanic Asian/Pacific Islander, non-Hispanic Black, Hispanic, non-Hispanic White), and sex (female, male). The rates and trends were estimated using a Bayesian spatiotemporal model and a smoothed over space, time, and demographic group. Rates are age-standardized in 10-year age groups using the 2010 US population. Data source: National Vital Statistics System.

  4. a

    U.S. Heart Disease Mortality 2019 - 2021

    • hub.arcgis.com
    Updated Jun 20, 2024
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    Centers for Disease Control and Prevention (2024). U.S. Heart Disease Mortality 2019 - 2021 [Dataset]. https://hub.arcgis.com/maps/cdcarcgis::u-s-heart-disease-mortality-2019-2021
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    Dataset updated
    Jun 20, 2024
    Dataset authored and provided by
    Centers for Disease Control and Prevention
    Area covered
    Description

    2019 - 2021, county-level U.S. heart disease death rates. Dataset developed by the Centers for Disease Control and Prevention, Division for Heart Disease and Stroke Prevention.Data SourceMortality data were obtained from the National Vital Statistics System. Bridged-Race Postcensal Population Estimates were obtained from the National Center for Health Statistics. International Classification of Diseases, 10th Revision (ICD-10) codes: I00-I09, I11, I13, I20-I51; underlying cause of death.Data DictionaryData for counties with small populations are not displayed when a reliable rate could not be generated. These counties are represented in the data with values of '-1.' CDC excludes these values when classifying the data on a map, indicating those counties as 'Insufficient Data.'Data field names and descriptionsstcty_fips: state FIPS code + county FIPS codeOther fields use the following format: RRR_S_aaaa (e.g., API_M_35UP)  RRR: 3 digits represent race/ethnicity    All - Overall    AIA - American Indian and Alaska Native, non-Hispanic    ASN - Asian, non-Hispanic    BLK - Black, non-Hispanic    HIS - Hispanic NHP – Native Hawaiian or Other Pacific Islander, non-Hispanic MOR – More than one race, non-Hispanic    WHT - White, non-Hispanic  S: 1 digit represents sex    A - All    F - Female    M - Male  aaaa: 4 digits represent age. The first 2 digits are the lower bound for age and the last 2 digits are the upper bound for age. 'UP' indicates the data includes the maximum age available and 'LT' indicates ages less than the upper bound. Example: The column 'BLK_M_65UP' displays rates per 100,000 black men aged 65 years and older.MethodologyRates are calculated using a 3-year average and are age-standardized in 10-year age groups using the 2000 U.S. Standard Population. Rates are calculated and displayed per 100,000 population. Rates were spatially smoothed using a Local Empirical Bayes algorithm to stabilize risk by borrowing information from neighboring geographic areas, making estimates more statistically robust and stable for counties with small populations. Data for counties with small populations are coded as '-1' when a reliable rate could not be generated. County-level rates were generated when the following criteria were met over a 3-year time period within each of the filters (e.g., age, race, and sex).At least one of the following 3 criteria:At least 20 events occurred within the county and its adjacent neighbors.ORAt least 16 events occurred within the county.ORAt least 5,000 population years within the county.AND all 3 of the following criteria:At least 6 population years for each age group used for age adjustment if that age group had 1 or more event.The number of population years in an age group was greater than the number of events.At least 100 population years within the county.More Questions?Interactive Atlas of Heart Disease and StrokeData SourcesStatistical Methods

  5. Deaths by heart diseases in the U.S. 1950-2019

    • statista.com
    Updated Jun 24, 2025
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    Statista (2025). Deaths by heart diseases in the U.S. 1950-2019 [Dataset]. https://www.statista.com/statistics/184515/deaths-by-heart-diseases-in-the-us-since-1950/
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    Dataset updated
    Jun 24, 2025
    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    United States
    Description

    The number of deaths caused by heart disease has decreased in the United States from ***** per 100,000 population in 1990 to ***** deaths per 100,000 population in 2019. Nevertheless, heart disease is still the leading cause of death in the country, followed closely by cancer, which has a mortality rate of ***** per 100,000 people. Heart disease in the U.S.Diseases of the heart and blood vessels are often associated with atherosclerosis, which occurs when plaque builds up along arterial walls. This can limit the flow of blood and can lead to blood clots, a common cause of stroke or heart attacks. Other types of heart disease include arrhythmia (abnormal heart rhythms) and heart valve problems. Many of these diseases can be treated with medication, although many complications will still remain. One of the leading cholesterol lowering drugs in the United States, Crestor, generated around **** billion U.S. dollars of revenue in 2024. Risk Factors for heart disease There are many risk factors associated with the development of heart disease, including family history, ethnicity, and age. However, there are other factors that can be modified through lifestyle changes such as physical inactivity, smoking, and unhealthy diets. Obesity has also been commonly associated with risk factors like hypertension and diabetes type II. In the United States, some ** percent of white adults are currently obese.

  6. a

    U.S. Stroke Mortality 2020-2022

    • hub.arcgis.com
    Updated Nov 29, 2024
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    Centers for Disease Control and Prevention (2024). U.S. Stroke Mortality 2020-2022 [Dataset]. https://hub.arcgis.com/datasets/e1a428474df841b49822b4fe59a47ef0
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    Dataset updated
    Nov 29, 2024
    Dataset authored and provided by
    Centers for Disease Control and Prevention
    Area covered
    Description

    2020 - 2022, county-level U.S. stroke death rates. Dataset developed by the Centers for Disease Control and Prevention, Division for Heart Disease and Stroke Prevention.Create maps of U.S. stroke death rates by county. Data can be stratified by age, race/ethnicity, and sex.Visit the CDC Atlas of Heart Disease and Stroke for additional data and maps. Atlas of Heart Disease and StrokeData SourceMortality data were obtained from the National Vital Statistics System. Bridged-Race Postcensal Population Estimates were obtained from the National Center for Health Statistics. International Classification of Diseases, 10th Revision (ICD-10) codes: I60-I69; underlying cause of death.Data DictionaryData for counties with small populations are not displayed when a reliable rate could not be generated. These counties are represented in the data with values of '-1.' CDC excludes these values when classifying the data on a map, indicating those counties as 'Insufficient Data.'Data field names and descriptionsstcty_fips: state FIPS code + county FIPS codeOther fields use the following format: RRR_S_aaaa (e.g., API_M_35UP)  RRR: 3 digits represent race/ethnicity    All - Overall    AIA - American Indian and Alaska Native, non-Hispanic    ASN - Asian, non-Hispanic    BLK - Black, non-Hispanic    HIS - Hispanic NHP – Native Hawaiian or Other Pacific Islander, non-Hispanic MOR – More than one race, non-Hispanic    WHT - White, non-Hispanic  S: 1 digit represents sex    A - All    F - Female    M - Male  aaaa: 4 digits represent age. The first 2 digits are the lower bound for age and the last 2 digits are the upper bound for age. 'UP' indicates the data includes the maximum age available and 'LT' indicates ages less than the upper bound. Example: The column 'BLK_M_65UP' displays rates per 100,000 black men aged 65 years and older.MethodologyRates are calculated using a 3-year average and are age-standardized in 10-year age groups using the 2000 U.S. Standard Population. Rates are calculated and displayed per 100,000 population. Rates were spatially smoothed using a Local Empirical Bayes algorithm to stabilize risk by borrowing information from neighboring geographic areas, making estimates more statistically robust and stable for counties with small populations. Data for counties with small populations are coded as '-1' when a reliable rate could not be generated. County-level rates were generated when the following criteria were met over a 3-year time period within each of the filters (e.g., age, race, and sex).At least one of the following 3 criteria:At least 20 events occurred within the county and its adjacent neighbors.ORAt least 16 events occurred within the county.ORAt least 5,000 population years within the county.AND all 3 of the following criteria:At least 6 population years for each age group used for age adjustment if that age group had 1 or more event.The number of population years in an age group was greater than the number of events.At least 100 population years within the county.More Questions?Interactive Atlas of Heart Disease and StrokeData SourcesStatistical Methods

  7. Leading Causes of Death US

    • kaggle.com
    Updated Jan 29, 2023
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    The Devastator (2023). Leading Causes of Death US [Dataset]. https://www.kaggle.com/datasets/thedevastator/leading-causes-of-death-us
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    CroissantCroissant is a format for machine-learning datasets. Learn more about this at mlcommons.org/croissant.
    Dataset updated
    Jan 29, 2023
    Dataset provided by
    Kaggle
    Authors
    The Devastator
    Area covered
    United States
    Description

    Leading Causes of Death US

    1980–2009 by Sex, Race, and Hispanic Origin

    By Health [source]

    About this dataset

    This fascinating dataset takes a look at the leading causes of death in the United States from 1980-2009, broken down by sex, race, and Hispanic origin. This data sheds light on how mortality in the US has changed over time among these categories. Accounting for everything from heart disease to cancer to suicide, this insight can be used by health researchers and policy makers to gain a better understanding of disparities in healthcare and deaths across different groups. Whether studying questions related to public health or more targeted population issues such as gender biases in death rates, this dataset provides an important resource for anyone interested in examining mortality across demographic lines

    More Datasets

    For more datasets, click here.

    Featured Notebooks

    • 🚨 Your notebook can be here! 🚨!

    How to use the dataset

    This dataset can be used to explore some of the leading causes of death in the United States from 1980 to 2009, broken down by sex, race, and Hispanic origin. This data can be used to better understand mortality trends and risk factors associated with different populations in America.

    By using this dataset you can compare and contrast mortality rates across different gender, racial, and ethnic groups during this time period. You can also compare different causes of death within these demographic categories to see if there are any patterns over time or notable differences between groups.

    You could even use this data to track changes across population groups as a whole or look at details for specific years or types of causes of death in particular groups. With this information one may gain insight into health disparities across population segments in America— aiding advocates for social change & public policy shifts toward improved health outcomes for all Americans!

    Research Ideas

    • Analyzing regional or state-level differences in mortality rates over time.
    • Examining the beahvioral factors or risk factors associated with each cause of death for different genders and populations.
    • Examining the prevalence of each cause of death as a proportion to an overall population trend in different socio-economic categories such as race or income level

    Acknowledgements

    If you use this dataset in your research, please credit the original authors. Data Source

    License

    License: Dataset copyright by authors - You are free to: - Share - copy and redistribute the material in any medium or format for any purpose, even commercially. - Adapt - remix, transform, and build upon the material for any purpose, even commercially. - You must: - Give appropriate credit - Provide a link to the license, and indicate if changes were made. - ShareAlike - You must distribute your contributions under the same license as the original. - Keep intact - all notices that refer to this license, including copyright notices.

    Columns

    File: Selected_Trend_Table_from_Health_United_States_2011._Leading_causes_of_death_and_numbers_of_deaths_by_sex_race_and_Hispanic_origin_United_States_1980_and_2009.csv | Column name | Description | |:-------------------|:---------------------------------------------------------------------------------------------------------| | Group | The group of people the cause of death applies to (e.g. men, women, whites, blacks, hispanics). (String) | | Year | The year the cause of death was recorded. (Integer) | | Cause of death | The cause of death. (String) | | Flag | A flag indicating whether the cause of death is considered a leading cause. (Boolean) | | Deaths | The number of deaths attributed to the cause of death. (Integer) |

    Acknowledgements

    If you use this dataset in your research, please credit the original authors. If you use this dataset in your research, please credit Health.

  8. a

    U.S. Heart Disease Mortality Rates 2016-2018

    • hub.arcgis.com
    • arc-gis-hub-home-arcgishub.hub.arcgis.com
    Updated May 28, 2020
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    Centers for Disease Control and Prevention (2020). U.S. Heart Disease Mortality Rates 2016-2018 [Dataset]. https://hub.arcgis.com/datasets/2b17d9d0f59f44b98ca65bd7333aa283
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    Dataset updated
    May 28, 2020
    Dataset authored and provided by
    Centers for Disease Control and Prevention
    License

    MIT Licensehttps://opensource.org/licenses/MIT
    License information was derived automatically

    Area covered
    Description

    Create maps of U.S. heart disease death rates by county. Data can be stratified by age, race/ethnicity, and sex. Visit the CDC/DHDSP Atlas of Heart Disease and Stroke for additional data and maps. Atlas of Heart Disease and StrokeData SourceMortality data were obtained from the National Vital Statistics System. Bridged-Race Postcensal Population Estimates were obtained from the National Center for Health Statistics. International Classification of Diseases, 10th Revision (ICD-10) codes: I00-I09, I11, I13, I20-I51; underlying cause of death.Data DictionaryData for counties with small populations are not displayed when a reliable rate could not be generated. These counties are represented in the data with values of '-1.' CDC/DHDSP excludes these values when classifying the data on a map, indicating those counties as 'Insufficient Data.' Data field names and descriptionsstcty_fips: state FIPS code + county FIPS codeOther fields use the following format: RRR_S_aaaa (e.g., API_M_35UP)   RRR: 3 digits represent race/ethnicity     All - Overall     AIA - American Indian and Alaska Native, non-Hispanic     API - Asian and Pacific Islander, non-Hispanic     BLK - Black, non-Hispanic     HIS - Hispanic     WHT - White, non-Hispanic   S: 1 digit represents sex     A - All    F - Female     M - Male aaaa: 4 digits represent age. The first 2 digits are the lower bound for age and the last 2 digits are the upper bound for age. 'UP' indicates the data includes the maximum age available and 'LT' indicates ages less than the upper bound.  Example: The column 'BLK_M_65UP' displays rates per 100,000 black men aged 65 years and older.MethodologyRates are calculated using a 3-year average and are age-standardized in 10-year age groups using the 2000 U.S. Standard Population. Rates are calculated and displayed per 100,000 population. Rates were spatially smoothed using a Local Empirical Bayes algorithm to stabilize risk by borrowing information from neighboring geographic areas, making estimates more statistically robust and stable for counties with small populations. Data for counties with small populations are coded as '-1' when a reliable rate could not be generated. County-level rates were generated when the following criteria were met over a 3-year time period within each of the filters (e.g., age, race, and sex).At least one of the following 3 criteria: At least 20 events occurred within the county and its adjacent neighbors.ORAt least 16 events occurred within the county.ORAt least 5,000 population years within the county.AND all 3 of the following criteria:At least 6 population years for each age group used for age adjustment if that age group had 1 or more event.The number of population years in an age group was greater than the number of events.At least 100 population years within the county.More Questions?Interactive Atlas of Heart Disease and StrokeData SourcesStatistical Methods

  9. g

    Rates and Trends in Hypertension-related Cardiovascular Disease Mortality...

    • gimi9.com
    Updated Feb 1, 2002
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    (2002). Rates and Trends in Hypertension-related Cardiovascular Disease Mortality Among US Adults (35+) by County, Age Group, Race/Ethnicity, and Sex – 2000-2019 | gimi9.com [Dataset]. https://gimi9.com/dataset/data-gov_2cf182609d59a8d09622c2047680a7967d1c085f/
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    Dataset updated
    Feb 1, 2002
    License

    Open Data Commons Attribution License (ODC-By) v1.0https://www.opendatacommons.org/licenses/by/1.0/
    License information was derived automatically

    Description

    This dataset documents rates and trends in local hypertension-related cardiovascular disease (CVD) death rates. Specifically, this report presents county (or county equivalent) estimates of hypertension-related CVD death rates in 2000-2019 and trends during two intervals (2000-2010, 2010-2019) by age group (ages 35–64 years, ages 65 years and older), race/ethnicity (non-Hispanic American Indian/Alaska Native, non-Hispanic Asian/Pacific Islander, non-Hispanic Black, Hispanic, non-Hispanic White), and sex (female, male). The rates and trends were estimated using a Bayesian spatiotemporal model and a smoothed over space, time, and demographic group. Rates are age-standardized in 10-year age groups using the 2010 US population. Data source: National Vital Statistics System.

  10. Leading causes of death, total population, by age group

    • www150.statcan.gc.ca
    • open.canada.ca
    Updated Feb 19, 2025
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    Government of Canada, Statistics Canada (2025). Leading causes of death, total population, by age group [Dataset]. http://doi.org/10.25318/1310039401-eng
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    Dataset updated
    Feb 19, 2025
    Dataset provided by
    Statistics Canadahttps://statcan.gc.ca/en
    Area covered
    Canada
    Description

    Rank, number of deaths, percentage of deaths, and age-specific mortality rates for the leading causes of death, by age group and sex, 2000 to most recent year.

  11. O

    Age-Adjusted Death Rates for Selected Leading Causes: 2005 - 2023

    • opendata.howardcountymd.gov
    csv, xlsx, xml
    Updated Jul 11, 2025
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    Howard County Health Department (2025). Age-Adjusted Death Rates for Selected Leading Causes: 2005 - 2023 [Dataset]. https://opendata.howardcountymd.gov/w/j7s2-ynf8/j72c-n6z5?cur=5XeND1_u0vf
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    csv, xlsx, xmlAvailable download formats
    Dataset updated
    Jul 11, 2025
    Dataset authored and provided by
    Howard County Health Department
    Description

    This data set includes age-adjusted death rates as published by the Vital Statistics Administration, Maryland Department of Health for both Maryland and Howard County. The rates are adjusted to the 2000 U.S. standard population by the direct method and are calculated per 100,000 population. Single year age-adjusted rates are available for the five (5) leading causes of death in Howard County for 2020 - Heart Diseases, Malignant Neoplasms (Cancer), COVID-19, Cerebrovascular Diseases, and Accidents; and for selected leading causes of death for years 2021 to 2023.

  12. f

    Snapshot of the bootstrap estimates of four predictors and the null factor...

    • plos.figshare.com
    xls
    Updated Feb 25, 2025
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    Roselinde Kessels; Chris Gotwalt; Guido Erreygers (2025). Snapshot of the bootstrap estimates of four predictors and the null factor for the first 16 data set replicates and epidemicity index I5 as response (Study I). A value of 0 means the variable is excluded from the model. [Dataset]. http://doi.org/10.1371/journal.pone.0318685.t004
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    xlsAvailable download formats
    Dataset updated
    Feb 25, 2025
    Dataset provided by
    PLOS ONE
    Authors
    Roselinde Kessels; Chris Gotwalt; Guido Erreygers
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    Snapshot of the bootstrap estimates of four predictors and the null factor for the first 16 data set replicates and epidemicity index I5 as response (Study I). A value of 0 means the variable is excluded from the model.

  13. Deaths from diseases of the heart

    • hub.arcgis.com
    • data-sccphd.opendata.arcgis.com
    Updated Feb 7, 2018
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    Santa Clara County Public Health (2018). Deaths from diseases of the heart [Dataset]. https://hub.arcgis.com/datasets/sccphd::deaths-from-diseases-of-the-heart
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    Dataset updated
    Feb 7, 2018
    Dataset provided by
    Santa Clara County Public Health Departmenthttps://publichealth.sccgov.org/
    Authors
    Santa Clara County Public Health
    License

    MIT Licensehttps://opensource.org/licenses/MIT
    License information was derived automatically

    Description

    Age-adjusted rate of death from diseases of the heart by sex, race/ethnicity, age; trends if available. Source: Santa Clara County Public Health Department, VRBIS, 2007-2016. Data as of 05/26/2017; U.S. Census Bureau; 2010 Census, Tables PCT12, PCT12H, PCT12I, PCT12J, PCT12K, PCT12L, PCT12M; generated by Baath M.; using American FactFinder; Accessed June 20, 2017. METADATA:Notes (String): Lists table title, notes and sourcesYear (Numeric): Year of dataCategory (String): Lists the category representing the data: Santa Clara County is for total population, sex: Male and Female, race/ethnicity: African American, Asian/Pacific Islander, Latino and White (non-Hispanic White only); age categories as follows: <1, 1 to 4, 5 to 14, 15 to 24, 25 to 34, 35 to 44, 45 to 54, 55 to 64, 65 to 74, 75 to 84, 85+; United StatesRate per 100,000 people (Numeric): Rate of deaths from diseases of the heart. Rates for age groups are reported as age-specific rates per 100,000 people. All other rates are age-adjusted rates per 100,000 people.

  14. f

    Table_1_Cause of Death During Renal Cell Carcinoma Survivorship: A...

    • frontiersin.figshare.com
    docx
    Updated Jun 1, 2023
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    Dong-Dong Yu; Wei-Kang Chen; Chen-Yu Wu; Wan-Ting Wu; Xiao Xin; Yu-Li Jiang; Peng Li; Ming-Hua Zhang (2023). Table_1_Cause of Death During Renal Cell Carcinoma Survivorship: A Contemporary, Population-Based Analysis.docx [Dataset]. http://doi.org/10.3389/fonc.2022.864132.s001
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    docxAvailable download formats
    Dataset updated
    Jun 1, 2023
    Dataset provided by
    Frontiers
    Authors
    Dong-Dong Yu; Wei-Kang Chen; Chen-Yu Wu; Wan-Ting Wu; Xiao Xin; Yu-Li Jiang; Peng Li; Ming-Hua Zhang
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    BackgroundAs the survival rates of patients with renal cell carcinoma (RCC) continue to increase, noncancer causes of death cannot be ignored. The cause-specific mortality in patients with RCC is not well understood.ObjectiveOur study aimed to explore the mortality patterns of contemporary RCC survivors.MethodsWe performed a retrospective cohort study involving patients with RCC from the Surveillance, Epidemiology, and End Results (SEER) database. We used standardized mortality ratios (SMRs) to compare the death rates in patients with RCC with those in the general population.ResultsA total of 106,118 patients with RCC, including 39,630 who died (27%), were included in our study. Overall, compared with the general US population, noncancer SMRs were increased 1.25-fold (95% confidence intervals [CI], 1.22 to 1.27; observed, 11,235), 1.19-fold (95% CI, 1.14 to 1.24; observed, 2,014), and 2.24-fold (95% CI, 2.11 to 2.38; observed, 1,110) for stage I/II, III, and IV RCC, respectively. The proportion of noncancer causes of death increased with the extension of survival time. A total of 4,273 men with stage I/II disease (23.13%) died of RCC; however, patients who died from other causes were 3.2 times more likely to die from RCC (n = 14,203 [76.87%]). Heart disease was the most common noncancer cause of death (n = 3,718 [20.12%]; SMR, 1.23; 95% CI, 1.19–1.27). In patients with stage III disease, 3,912 (25.98%) died from RCC, and 2,014 (13.37%) died from noncancer causes. Most patients (94.99%) with stage IV RCC died within 5 years of initial diagnosis. Although RCC was the leading cause of death (n = 12,310 [84.65%]), patients with stage IV RCC also had a higher risk of noncancer death than the general population (2.24; 95% CI, 2.11–2.38).ConclusionsNon-RCC death causes account for more than 3/4 of RCC survivors among patients with stage I/II disease. Patients with stage IV are most likely to die of RCC; however, there is an increased risk of dying from septicemia, and suicide cannot be ignored. These data provide the latest and most comprehensive assessment of the causes of death in patients with RCC.

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Centers for Disease Control and Prevention (2025). Rates and Trends in Heart Disease and Stroke Mortality Among US Adults (35+) by County, Age Group, Race/Ethnicity, and Sex – 2000-2019 [Dataset]. https://catalog.data.gov/dataset/rates-and-trends-in-heart-disease-and-stroke-mortality-among-us-adults-35-by-county-a-2000-45659
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Rates and Trends in Heart Disease and Stroke Mortality Among US Adults (35+) by County, Age Group, Race/Ethnicity, and Sex – 2000-2019

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Dataset updated
Jun 28, 2025
Dataset provided by
Centers for Disease Control and Preventionhttp://www.cdc.gov/
Description

This dataset documents rates and trends in heart disease and stroke mortality. Specifically, this report presents county (or county equivalent) estimates of heart disease and stroke death rates in 2000-2019 and trends during two intervals (2000-2010, 2010-2019) by age group (ages 35–64 years, ages 65 years and older), race/ethnicity (non-Hispanic American Indian/Alaska Native, non-Hispanic Asian/Pacific Islander, non-Hispanic Black, Hispanic, non-Hispanic White), and sex (women, men). The rates and trends were estimated using a Bayesian spatiotemporal model and a smoothed over space, time, and demographic group. Rates are age-standardized in 10-year age groups using the 2010 US population. Data source: National Vital Statistics System.

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